Disease: Unipolar Depression
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
INS P01308 insulin 0.30 0.445 0.923
LEP P41159 leptin 0.46 0.349 0.846
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
PLA2G2A P14555 phospholipase A2 group IIA Enzyme 9.7E-02 0.488 0.808
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PVALB P20472 parvalbumin Calcium-binding protein 8.7E-02 0.547 0.692
RGS4 P49798 regulator of G protein signaling 4 Enzyme modulator 5.1E-08 0.621 0.577