|
rs9904341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, we found that the survivin rs9904341 polymorphism was associated with an increased risk of acute pancreatitis.
|
26125713 |
2015 |
|
rs778574118
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men.
|
27984487 |
2017 |
|
rs1052571
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05).
|
27984487 |
2017 |
|
rs1132312
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CASP9 Phe136Leu/Phe136Phe SNPs (heterozygotes) increases the risk for mild AP (odds ratio, 3.616; 95% confidence interval, 1.151-11.364; P < 0.05), whereas the homozygotic genotype of CASP9 Ala28Val decreases risk for mild AP (odds ratio, 0.296; 95% confidence interval, 0.091-0.963; P < 0.05).
|
27984487 |
2017 |
|
rs78655421
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the aim of our study was to determine the functional importance of common cystic fibrosis transmembrane conductance regulator variations IVS8-poly T, R117H, and M470V for the severity of acute pancreatitis.
|
30132293 |
2019 |
|
rs213950
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the aim of our study was to determine the functional importance of common cystic fibrosis transmembrane conductance regulator variations IVS8-poly T, R117H, and M470V for the severity of acute pancreatitis.
|
30132293 |
2019 |
|
rs7057398
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Meta-analyses of all AP patients depicted significant (p-value < 0.05) associations for rs10273639 (odds ratio (OR) 0.88, 95% confidence interval (CI) 0.81-0.97, p-value 0.01), rs7057398 (OR 1.27, 95% CI 1.07-1.5, p-value 0.005), and rs12688220 (OR 1.32, 95% CI 1.12-1.56, p-value 0.001).
|
29884332 |
2018 |
|
rs7057398
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our findings suggested that rs7057398, rs12688220 and rs10273639 polymorphisms could be used to identify individuals at an elevated susceptibility to acute pancreatitis in Caucasians.
|
31163246 |
2020 |
|
rs777418530
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SPINK1 N34S mutation enhances the susceptibility of AP.
|
15782101 |
2005 |
|
rs777418530
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The SPINK1 N34S variant is associated with acute pancreatitis.
|
18617776 |
2008 |
|
rs497078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to determine the relationship between the presence of p.G60 = polymorphism (c.180C > T; rs497078) CTRC and the incidence together with the clinical course of acute pancreatitis (AP).
|
28095786 |
2017 |
|
rs4073
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This meta-analysis demonstrated a suggestive result that people who carried the risk A allele of the IL-8 rs4073 polymorphism may be more sensitive to acute pancreatitis.
|
31340771 |
2019 |
|
rs4073
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The results showed evidence for significant association between IL-8 -251 T/A (rs4073) polymorphism and AP risk, suggesting that IL-8 -251 A allele was associated with an increased risk of AP (for A allele vs. T allele: OR = 1.36, 95 % CI 1.05-1.76, p = 0.02; for A/A vs. T/T: OR = 2.28, 95 % CI 1.08-4.81, p = 0.03; for A/A+T/A vs. T/T: OR = 1.40, 95 % CI 1.11-1.77, p = 0.005).
|
24072654 |
2013 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of GSTM1 is associated with increased susceptibility for AP, and the GSTP1 Val105Ile SNP is associated with an increased risk for AP in men.
|
27984487 |
2017 |
|
rs2071746
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The GT-repeat and SNP rs2071746 were investigated with fluorescence labelled primers and by melting curve analysis in 285 patients with acute pancreatitis, 208 patients with alcoholic CP, 207 patients with idiopathic/hereditary CP, 147 patients with alcoholic liver cirrhosis, and in 289 controls, respectively.
|
22666428 |
2012 |
|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In a dominant model, we found that the GA+AA genotype of IL-10 rs1800896 was associated with an elevated risk of acu</span>te pancreatitis (OR = 1.51, 95%CI = 1.05-2.18).
|
26634555 |
2015 |
|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, there were no significant associations between IL-1β (IL-1β +3954 C/T (rs1143634) and IL-1β -511 C/T (rs16944)), IL-6 (IL-6 -174 G/C (rs1800795) and IL-6 -634 C/G (rs1800796)) and IL-10 (IL-10 -1082 A/G (rs1800896), IL-10 -819 C/T (rs1800871) and IL-10 -592 C/A (rs1800872)) gene polymorphisms and AP risk.
|
24072654 |
2013 |
|
rs1800896
|
|
|
0.030 |
GeneticVariation |
BEFREE |
IL-10 gene rs1800896 polymorphism increases the risk of AP.
|
29310417 |
2017 |
|
rs1800871
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, there were no significant associations between IL-1β (IL-1β +3954 C/T (rs1143634) and IL-1β -511 C/T (rs16944)), IL-6 (IL-6 -174 G/C (rs1800795) and IL-6 -634 C/G (rs1800796)) and IL-10 (IL-10 -1082 A/G (rs1800896), IL-10 -819 C/T (rs1800871) and IL-10 -592 C/A (rs1800872)) gene polymorphisms and AP risk.
|
24072654 |
2013 |
|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, there were no significant associations between IL-1β (IL-1β +3954 C/T (rs1143634) and IL-1β -511 C/T (rs16944)), IL-6 (IL-6 -174 G/C (rs1800795) and IL-6 -634 C/G (rs1800796)) and IL-10 (IL-10 -1082 A/G (rs1800896), IL-10 -819 C/T (rs1800871) and IL-10 -592 C/A (rs1800872)) gene polymorphisms and AP risk.
|
24072654 |
2013 |
|
rs1143634
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Multivariate regression analyses showed that subjects carrying the rs1143634 TT genotype had a significantly increased risk of acute pancreatitis, with an adjusted odds ratio (95% confidence interval) of 2.11 (1.03-4.51).
|
25730036 |
2015 |
|
rs1143634
|
|
|
0.020 |
GeneticVariation |
BEFREE |
However, there were no significant associations between IL-1β (IL-1β +3954 C/T (rs1143634) and IL-1β -511 C/T (rs16944)), IL-6 (IL-6 -174 G/C (rs1800795) and IL-6 -634 C/G (rs1800796)) and IL-10 (IL-10 -1082 A/G (rs1800896), IL-10 -819 C/T (rs1800871) and IL-10 -592 C/A (rs1800872)) gene polymorphisms and AP risk.
|
24072654 |
2013 |
|
rs16944
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, there were no significant associations between IL-1β (IL-1β +3954 C/T (rs1143634) and IL-1β -511 C/T (rs16944)), IL-6 (IL-6 -174 G/C (rs1800795) and IL-6 -634 C/G (rs1800796)) and IL-10 (IL-10 -1082 A/G (rs1800896), IL-10 -819 C/T (rs1800871) and IL-10 -592 C/A (rs1800872)) gene polymorphisms and AP risk.
|
24072654 |
2013 |
|
rs4251961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL1RN -1129T>C (rs4251961) genotypes might be associated with a significant increase of AP risk in a Korean ethnic group.
|
29117667 |
2018 |
|
rs11209026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Epistasis analysis revealed that AP susceptibility was increased by interaction between <i>IL23R</i> rs11209026 and <i>TNF</i> rs1800629 (p = 1.205 × 10<sup>-5</sup>; OR<sub>interaction</sub> = 4.031).
|
31044631 |
2019 |