|
rs1614972
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Despite a number of potential differences between the samples investigated by the prior GWAS and the current study, data presented here provide additional support for the association of SNP rs1614972 in ADH1C with alcohol dependence and extend this finding by demonstrating association with consumption levels in both non-alcoholic and alcohol-dependent populations.
|
23516558 |
2013 |
|
rs698
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Three single nucleotide polymorphisms (SNPs) in alcohol-metabolizing genes - ADH1B (Arg47His), ADH1C (Ile350Val) and ALDH2 (Glu504Lys) have been extensively associated with flush reaction and alcoholism.
|
28610454 |
2018 |
|
rs698
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The interactions of religious involvement with ADH1B-rs2066702, ADH1C-rs698, and ADH4-rs1042364 were significantly associated with maximum drinks and alcohol dependence symptoms.
|
27172571 |
2016 |
|
rs698
|
|
|
0.050 |
GeneticVariation |
BEFREE |
To evaluate the association between the alcohol dehydrogenase 1C (ADH1C) Ile350Val and aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphisms and alcohol dependence in a Turkish sample.
|
25372623 |
2015 |
|
rs698
|
|
|
0.050 |
GeneticVariation |
BEFREE |
No profound connection between alcohol dependence and ADH1C Ile350Val gene polymorphism was detected.
|
22325912 |
2012 |
|
rs698
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The results showed strong evidence of association between ADH1C Ile350Val (rs698, formerly ADH1C *1/*2) and alcohol dependence (AD) and abuse in the combined studies.
|
22476623 |
2012 |
|
rs35385902
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Three single nucleotide polymorphisms (SNPs) in alcohol-metabolizing genes - ADH1B (Arg47His), ADH1C (Ile350Val) and ALDH2 (Glu504Lys) have been extensively associated with flush reaction and alcoholism.
|
28610454 |
2018 |
|
rs35385902
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this article we present summaries of previous studies and of the present study, to give an overview of the worldwide effects of ADH1B His47Arg on the risk of alcoholism.
|
16086315 |
2005 |
|
rs4147541
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three mQTLs (rs2173201, rs4147542, and rs4147541 in ADH1B-AHD1C gene cluster region) found in AAs were previously identified by our genome-wide association studies as being significantly associated with AD in AAs.
|
24889829 |
2014 |
|
rs4147542
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three mQTLs (rs2173201, rs4147542, and rs4147541 in ADH1B-AHD1C gene cluster region) found in AAs were previously identified by our genome-wide association studies as being significantly associated with AD in AAs.
|
24889829 |
2014 |
|
rs1693482
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Numerous SNPs in ADH genes showed association with AD, including one marker in the coding region of ADH1C (rs1693482 in exon6, Ile271Gln).
|
18331377 |
2008 |