|
rs2071346
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found rs2071346 (G>T) variant genotype carriers were subjected to higher risk of anemia (GT <i>vs</i> GG, OR=1.665, P=0.022) and thrombocytopenia (GT <i>vs</i> GG, OR=1.685, P=0.035).
|
30662535 |
2019 |
|
rs377001714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We present a 20-year-old male with a novel c.461T>C (p.L154P) PGK1 mutation and clinical disease complicated by anemia and neurological symptoms.
|
30951021 |
2019 |
|
rs41518645
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Non-synonymous substitutions (F33 L and D171N) and Indel mutations were observed for Cytochrome B gene, leading to a truncated protein, where anemia, malfunctioning of most of the vital organs as liver, kidney and mineral status was observed and debility with exercise intolerance and cardiomyopathy in extreme cases were depicted.
|
30660753 |
2019 |
|
rs4645948
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, rs4645948 (C>T) was conferred with increased risk of anemia (CT <i>vs</i> CC, OR=2.152, P=0.001) and severe leukopenia (CT <i>vs</i> CC, OR=1.893, P=0.034) for NPC patients receiving chemoradiotherapy.
|
30662535 |
2019 |
|
rs121908117
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Anaemia in TREX1 D18N mice is accompanied by increased erythropoietin (Epo), normal hepcidin levels and the TREX1 D18N mice display an inappropriate response to anaemic challenge.
|
30422000 |
2018 |
|
rs1801133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms of the genes MTHFR (rs1801133) and APOA5 (rs662799), as well as anemia, are independent risk factors for stroke in Mexicans, together with traditional cardiovascular risk factors such as high triglycerides and high blood pressure.
|
29398535 |
2018 |
|
rs2245214
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The variant allele of rs6568431 SNP was more present in patients with anemia (OR = 1.86, p = 0.009) and renal involvement (OR = 1.63, p = 0.06), while the variant allele of rs2245214 SNP was significantly associated with a higher risk of producing anti-DNA autoantibodies (OR = 1.66, p = 0.04).
|
29759048 |
2018 |
|
rs267607201
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The child with unexplained anemia had c.973G>A (p.Glu325Lys), associated with congenital dyserythropoietic anemia.
|
29047116 |
2018 |
|
rs6568431
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The variant allele of rs6568431 SNP was more present in patients with anemia (OR = 1.86, p = 0.009) and renal involvement (OR = 1.63, p = 0.06), while the variant allele of rs2245214 SNP was significantly associated with a higher risk of producing anti-DNA autoantibodies (OR = 1.66, p = 0.04).
|
29759048 |
2018 |
|
rs662799
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms of the genes MTHFR (rs1801133) and APOA5 (rs662799), as well as anemia, are independent risk factors for stroke in Mexicans, together with traditional cardiovascular risk factors such as high triglycerides and high blood pressure.
|
29398535 |
2018 |
|
rs10132552
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The most dramatic finding was that the MEG3 rs10132552 CC genotype had a greater than three-fold increased risk of developing grade 3-4 anaemia (OR = 3.001, 95%CI = 1.355-6.646, P = 0.007).
|
28814798 |
2017 |
|
rs10761745
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found significant interaction effects between rs10761745 (JMJD1C) and average hemoglobin levels on the risk of T2D among women with normal inflammation and without anemia at baseline.
|
28406950 |
2017 |
|
rs1470452230
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ITPA gene polymorphism (94C>A) effects on ribavirin-induced anemia during therapy in Egyptian patients with chronic hepatitis C.
|
28480960 |
2017 |
|
rs1884444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression analysis, controlling for confounding factor of anemia, revealed that individual genotypes of IL-23R rs1884444 (G/T) [GT; OR = 1.34, 95% CI = 0.78-2.31, P = 0.304 and TT; OR = 2.02, 95% CI = 0.53-7.74, P = 0.286] and IL-23R rs7530511 (C/T) [CT; OR = 2.6, 95% CI = 0.59-11.86, P = 0.202 and TT; OR = 1.66, 95% CI = 0.84-3.27, P = 0.142] were not associated with susceptibility to SMA.
|
28427357 |
2017 |
|
rs4150558
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association with anemia and neutropenia were found in GP regimen. rs4150558 showed significant association with anemia in NP regimen.
|
28924235 |
2017 |
|
rs559063155
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts.
|
27604819 |
2017 |
|
rs7530511
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression analysis, controlling for confounding factor of anemia, revealed that individual genotypes of IL-23R rs1884444 (G/T) [GT; OR = 1.34, 95% CI = 0.78-2.31, P = 0.304 and TT; OR = 2.02, 95% CI = 0.53-7.74, P = 0.286] and IL-23R rs7530511 (C/T) [CT; OR = 2.6, 95% CI = 0.59-11.86, P = 0.202 and TT; OR = 1.66, 95% CI = 0.84-3.27, P = 0.142] were not associated with susceptibility to SMA.
|
28427357 |
2017 |
|
rs866082104
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts.
|
27604819 |
2017 |
|
rs1143634
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover IL1B rs1143634 resulted significantly associated to patients' parasitaemia, while IL18 rs5744256 plays a protective role against the development of anaemia.
|
26946405 |
2016 |
|
rs3024505
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In contrast, CD patients carrying C allele of rs3024505 had significantly increased risk of anemia and stricturing/penetrating behavior.
|
27558476 |
2016 |
|
rs5744256
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover IL1B rs1143634 resulted significantly associated to patients' parasitaemia, while IL18 rs5744256 plays a protective role against the development of anaemia.
|
26946405 |
2016 |
|
rs1128503
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The risk of anemia was increased for variant alleles of rs1128503 (ABCB1, C > T; p = 0.023, OR = 1.71, 95% CI = 1.07-2.71), rs363717 (ABCA1, A > G; p = 0.002, OR = 2.08, 95% CI = 1.32-3.27) and rs11615 (ERCC1, T > C; p = 0.031, OR = 1.61, 95% CI = 1.04-2.50), while it was decreased for variant alleles of rs12762549 (ABCC2, C > G; p = 0.004, OR = 0.51, 95% CI = 0.33-0.81).
|
25881102 |
2015 |
|
rs11615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The risk of anemia was increased for variant alleles of rs1128503 (ABCB1, C > T; p = 0.023, OR = 1.71, 95% CI = 1.07-2.71), rs363717 (ABCA1, A > G; p = 0.002, OR = 2.08, 95% CI = 1.32-3.27) and rs11615 (ERCC1, T > C; p = 0.031, OR = 1.61, 95% CI = 1.04-2.50), while it was decreased for variant alleles of rs12762549 (ABCC2, C > G; p = 0.004, OR = 0.51, 95% CI = 0.33-0.81).
|
25881102 |
2015 |
|
rs12762549
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The risk of anemia was increased for variant alleles of rs1128503 (ABCB1, C > T; p = 0.023, OR = 1.71, 95% CI = 1.07-2.71), rs363717 (ABCA1, A > G; p = 0.002, OR = 2.08, 95% CI = 1.32-3.27) and rs11615 (ERCC1, T > C; p = 0.031, OR = 1.61, 95% CI = 1.04-2.50), while it was decreased for variant alleles of rs12762549 (ABCC2, C > G; p = 0.004, OR = 0.51, 95% CI = 0.33-0.81).
|
25881102 |
2015 |
|
rs13194491
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The risk of developing anaemia is increased in reproductive age women carriers of A allele of rs1868505 (CACNA2D3) and/or T allele of rs13194491 (HIST1H2BJ).
|
26460247 |
2015 |