|
rs16966671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No statistically significant difference was demonstrated in either the allele or genotype frequencies of the other four examined SNPs (rs13306296, rs4673, rs9932581, and rs16966671) between the CWP group and dust-exposed control group (all p > .05).
|
30654669 |
2019 |
|
rs7195830
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using the additive and the dominant model, the CYBA SNP rs7195830 polymorphism also showed significant associations with CWP patients (p < .001, OR = 1.621; p = .003, OR = 1.711, respectively).
|
30654669 |
2019 |
|
rs1667614
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found 4 CWP risk-associated eQTL SNPs, including rs10797062 at 1q23.2 (p = 6.91 × 10-4, OR = 1.28), rs1667614 at 2q13.1 (p = 1.48 × 10-4, OR = 0.53), rs2540438 at 2q33.1 (p = 2.13 × 10-3, OR = 1.33), and rs2274554 at 13q31.1 (p = 9.01 × 10-5, OR = 1.35).
|
29394417 |
2018 |
|
rs2274554
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found 4 CWP risk-associated eQTL SNPs, including rs10797062 at 1q23.2 (p = 6.91 × 10-4, OR = 1.28), rs1667614 at 2q13.1 (p = 1.48 × 10-4, OR = 0.53), rs2540438 at 2q33.1 (p = 2.13 × 10-3, OR = 1.33), and rs2274554 at 13q31.1 (p = 9.01 × 10-5, OR = 1.35).
|
29394417 |
2018 |
|
rs2540438
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found 4 CWP risk-associated eQTL SNPs, including rs10797062 at 1q23.2 (p = 6.91 × 10-4, OR = 1.28), rs1667614 at 2q13.1 (p = 1.48 × 10-4, OR = 0.53), rs2540438 at 2q33.1 (p = 2.13 × 10-3, OR = 1.33), and rs2274554 at 13q31.1 (p = 9.01 × 10-5, OR = 1.35).
|
29394417 |
2018 |
|
rs2290846
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, the polymorphism of rs2290846 decreased the CWP risk among cases over 27 years of dust exposure (adjusted OR = 0.51, 95% CI = 0.28-0.94) and non-smokers (adjusted OR = 0.58, 95% CI = 0.34-1.00).
|
28953250 |
2017 |
|
rs2067051
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that rs2067051 in the H19 gene is correlated with a deceased risk of CWP in</span> a Chinese population, which may be a potential genetic marker for prevention and intervention of CWP.
|
27626436 |
2016 |
|
rs10502001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that three functional SNPs (MMP-7 rs10502001, OPN rs11728697 and OPN rs1126772) are associated with an increased risk of CWP in a Chinese population.
|
26330178 |
2015 |
|
rs1126772
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that three functional SNPs (MMP-7 rs10502001, OPN rs11728697 and OPN rs1126772) are associated with an increased risk of CWP in a Chinese population.
|
26330178 |
2015 |
|
rs11728697
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate that three functional SNPs (MMP-7 rs10502001, OPN rs11728697 and OPN rs1126772) are associated with an increased risk of CWP in a Chinese population.
|
26330178 |
2015 |
|
rs1799750
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association of three functional polymorphisms in MMP gene promoters (MMP1 rs1799750, MMP2 rs2285053 and MMP3 rs522616) with the risk of CWP.
|
26528997 |
2015 |
|
rs2285053
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association of three functional polymorphisms in MMP gene promoters (MMP1 rs1799750, MMP2 rs2285053 and MMP3 rs522616) with the risk of CWP.
|
26528997 |
2015 |
|
rs3748067
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs3748067 G > A and rs8193036 C > T polymorphisms decrease CWP risk.
|
26223249 |
2015 |
|
rs3748076
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Unconditional logistic regression analysis showed that the genotypes of rs3748067 AA (adjusted OR = 0.43, 95 % CI = 0.23-0.83) and rs8193036 TT (adjusted OR = 0.59, 95 % CI = 0.40-0.86) were associated with a decreased risk of CWP, particularly among subgroups of smokers (adjusted OR =0.34, 95 % CI = 0.13-0.86 for rs3748076; adjusted OR = 0.41, 95 % CI = 0.23-0.71 for 8193036) and CWP cases with stage I (adjusted OR = 0.45, 95 % CI = 0.21-0.98 for rs3748076; adjusted OR = 0.46, 95 % CI = 0.28-0.74 for 8193036).
|
26223249 |
2015 |
|
rs522616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings indicate that the MMP3 rs522616 polymorphism may contribute to the etiology of CWP in the Chinese population and MMP3 might be a potential diagnostic biomarker for CWP, additional independent studies are warranted to validate our findings in different populations as well as in a larger series.
|
26528997 |
2015 |
|
rs8193036
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs3748067 G > A and rs8193036 C > T polymorphisms decrease CWP risk.
|
26223249 |
2015 |
|
rs1053411
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results revealed that three SNPs (rs1059279, rs1059829, rs1053411) were significantly associated with increased risk of CWP under an additive model (OR = 1.35, 95%CI = 1.06-1.71, P = 0.015 for rs1059279; OR = 1.20, 95%CI = 1.03-1.39, P = 0.021 for rs1059829; OR = 1.31, 95%CI = 1.03-1.65, P = 0.025 for rs1053411).
|
25126876 |
2014 |
|
rs1059279
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results revealed that three SNPs (rs1059279, rs1059829, rs1053411) were significantly associated with increased risk of CWP under an additive model (OR = 1.35, 95%CI = 1.06-1.71, P = 0.015 for rs1059279; OR = 1.20, 95%CI = 1.03-1.39, P = 0.021 for rs1059829; OR = 1.31, 95%CI = 1.03-1.65, P = 0.025 for rs1053411).
|
25126876 |
2014 |
|
rs1059829
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results revealed that three SNPs (rs1059279, rs1059829, rs1053411) were significantly associated with increased risk of CWP under an additive model (OR = 1.35, 95%CI = 1.06-1.71, P = 0.015 for rs1059279; OR = 1.20, 95%CI = 1.03-1.39, P = 0.021 for rs1059829; OR = 1.31, 95%CI = 1.03-1.65, P = 0.025 for rs1053411).
|
25126876 |
2014 |
|
rs11466668
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association study analyzing three polymorphisms (rs3753348, rs2298213, and rs11466668) in GITR were performed in a case-control study including 693 patients with CWP and 690 controls.
|
25445616 |
2014 |
|
rs20417
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cyclooxygenase-2 rs689466 and rs20417 polymorphisms were associated with CWP risk.
|
24899082 |
2014 |
|
rs2672794
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is the first report showing an association between the MUC5B rs2672794 polymorphism and CWP, and our results suggest that MUC5B rs2672794 CC genotype could increase the risk of CWP.
|
24924948 |
2014 |
|
rs3753348
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is the first report revealing an association between the GITR rs3753348 polymorphism and CWP, and our results suggest that the GITR rs3753348 polymorphism may be involved in the development and susceptibility of CWP.
|
25445616 |
2014 |
|
rs689466
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cyclooxygenase-2 rs689466 and rs20417 polymorphisms were associated with CWP risk.
|
24899082 |
2014 |
|
rs5368
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggest that the T1559C/rs5368 polymorphism and smoking are involved in the susceptibility to CWP.
|
24066042 |
2013 |