Gene: LMNA ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs57920071
rs57920071
LMNA
0.020 GeneticVariation BEFREE The p.R482W hotspot mutation in A-type nuclear lamins causes familial partial lipodystrophy of Dunnigan-type (FPLD2), a lipodystrophic syndrome complicated by early onset atherosclerosis. 29438482

2018
dbSNP: rs57920071
rs57920071
LMNA
0.020 GeneticVariation BEFREE Lipodystrophy-linked LMNA p.R482W mutation induces clinical early atherosclerosis and in vitro endothelial dysfunction. 23846499

2013
dbSNP: rs797044485
rs797044485
LMNA
0.010 GeneticVariation BEFREE We report a novel lamin A/C (LMNA) mutation, p.Glu223Lys, in a family with extensive atherosclerosis, diabetes mellitus and steatosis hepatis. 23659872

2013
dbSNP: rs80356814
rs80356814
LMNA
0.010 GeneticVariation BEFREE The LMNA 1908C/T polymorphism has been reported to be associated with dyslipidaemia, metabolic syndrome, adipose tissue metabolism and obesity phenotypes, suggesting that this polymorphism presents an increased risk of atherosclerosis and vascular diseases. 16117820

2005