|
rs743777
|
|
|
0.820 |
GeneticVariation |
BEFREE |
To assess the impact of single nucleotide polymorphisms (SNPs) in IL-2RA (rs2104286) and IL-2RB (rs743777 and rs3218253) genes on the risk of erosions in rheumatoid arthritis (RA) patients.
|
24200909 |
2014 |
|
rs743777
|
|
|
0.820 |
GeneticVariation |
BEFREE |
We investigated a possilbe association between SNPs in IL-2RA and IL-2RB genes and RA in a Han Chinese population. rs2104286 in IL-2RA and rs743777 in IL-2RB genes were genotyped in a Han Chinese cohort composed of 500 patients with RA and 600 controls.
|
23512675 |
2013 |
|
rs743777
|
|
G |
0.820 |
GeneticVariation |
GWASCAT |
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
|
17554300 |
2007 |
|
rs743777
|
|
G |
0.820 |
GeneticVariation |
GWASDB |
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
|
17554300 |
2007 |
|
rs3218251
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.
|
24532676 |
2015 |
|
rs3218251
|
|
|
0.800 |
GeneticVariation |
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
rs3218251
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
rs3218253
|
|
|
0.720 |
GeneticVariation |
BEFREE |
To assess the impact of single nucleotide polymorphisms (SNPs) in IL-2RA (rs2104286) and IL-2RB (rs743777 and rs3218253) genes on the risk of erosions in rheumatoid arthritis (RA) patients.
|
24200909 |
2014 |
|
rs3218253
|
|
|
0.720 |
GeneticVariation |
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
rs3218253
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Here we show that three of these SNPs, mapping to chromosome 10p15 (rs4750316), 12q13 (rs1678542) and 22q13 (rs3218253), are also associated (trend P = 4 x 10(-5), P = 4 x 10(-4) and P = 4 x 10(-4), respectively) in a validation study of 4,106 individuals with rheumatoid arthritis and an expanded reference group of 11,238 subjects, confirming them as true susceptibility loci in individuals of European ancestry.
|
18794857 |
2008 |
|
rs2281089
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification analysis revealed that two SNPs (rs791588 and rs2281089) were significantly associated with a reduced RA risk in an allele and genetic model after stratification by gender or age (p < 0.05).
|
31134763 |
2019 |