rs2275913
|
|
|
0.070 |
GeneticVariation |
BEFREE |
IL-17A rs2275913 and IL-17F rs763780 polymorphisms are significantly associated with susceptibility to RA and with different clinical characteristics of this disease.
|
31454755 |
2020 |
rs2275913
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate whether the IL-17A -737 T/C (rs8193036), -444A/G (rs3819024), -197G/A (rs2275913), and -121G/A (rs8193037) SNPs conferred susceptibility to SLE (or lupus nephritis) or to RA in a Mexican population.
|
30398030 |
2019 |
rs2275913
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Knowing this, the aim of this study was to investigate the association of +2199 A/C IL-23R (rs10889677), -197 G/A IL-17A (rs2275913), and +7488 A/G IL-17F (rs763780) gene polymorphisms with RA susceptibility and clinical features in a Brazilian population.
|
28547498 |
2017 |
rs2275913
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We found evidence of associations between RA and alleles from the <i>IL-17A</i> rs2275913 and <i>IL-17F</i> rs763780 polymorphisms in Caucasians (p=0.003 and p=0.037, respectively).
|
28069745 |
2017 |
rs2275913
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In summary, our pooled analysis indicated that the IL-17A (rs2275913) and IL17F (rs763780 T/C) increased the RA risk.
|
28186427 |
2017 |
rs2275913
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our results indicated that IL17A rs4711998 A/G and IL17A rs8193037 G/A polymorphisms were not associated with RA, and IL17A rs2275913 G/A and IL17A rs3819024 A/G variant alleles decrease the risk of RA, while IL17A rs3819025 G/A and IL17A rs8193036 C/T variant alleles increase the risk of RA.
|
25871515 |
2015 |
rs2275913
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The present study aimed to determine the association between the polymorphic variants of the IL-17A (rs2275913), IL-17F (rs763780) and IL-23R (rs11209026) genes and RA susceptibility, progression and response to therapy with TNF-α inhibitors.
|
25387578 |
2015 |
rs3819024
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate whether the IL-17A -737 T/C (rs8193036), -444A/G (rs3819024), -197G/A (rs2275913), and -121G/A (rs8193037) SNPs conferred susceptibility to SLE (or lupus nephritis) or to RA in a Mexican population.
|
30398030 |
2019 |
rs8193036
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate whether the IL-17A -737 T/C (rs8193036), -444A/G (rs3819024), -197G/A (rs2275913), and -121G/A (rs8193037) SNPs conferred susceptibility to SLE (or lupus nephritis) or to RA in a Mexican population.
|
30398030 |
2019 |
rs3819024
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our meta-analysis revealed significantly higher circulating IL-17 levels in patients with RA, and found evidence of associations between the <i>IL-17A</i> rs2275913, <i>IL-17F</i> rs763780 and <i>IL-17A</i> rs3819024 polymorphisms and pathogenesis of RA.
|
28069745 |
2017 |
rs8193036
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, no evidence of association was found between the <i>IL-17F</i> rs2397084, <i>IL-17A</i> rs4711998 and <i>IL-17A</i> rs8193036 polymorphisms and RA susceptibility.
|
28069745 |
2017 |
rs3819024
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results indicated that IL17A rs4711998 A/G and IL17A rs8193037 G/A polymorphisms were not associated with RA, and IL17A rs2275913 G/A and IL17A rs3819024 A/G variant alleles decrease the risk of RA, while IL17A rs3819025 G/A and IL17A rs8193036 C/T variant alleles increase the risk of RA.
|
25871515 |
2015 |
rs8193036
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results indicated that IL17A rs4711998 A/G and IL17A rs8193037 G/A polymorphisms were not associated with RA, and IL17A rs2275913 G/A and IL17A rs3819024 A/G variant alleles decrease the risk of RA, while IL17A rs3819025 G/A and IL17A rs8193036 C/T variant alleles increase the risk of RA.
|
25871515 |
2015 |
rs8193037
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate whether the IL-17A -737 T/C (rs8193036), -444A/G (rs3819024), -197G/A (rs2275913), and -121G/A (rs8193037) SNPs conferred susceptibility to SLE (or lupus nephritis) or to RA in a Mexican population.
|
30398030 |
2019 |
rs4711998
|
|
|
0.020 |
GeneticVariation |
BEFREE |
However, no evidence of association was found between the <i>IL-17F</i> rs2397084, <i>IL-17A</i> rs4711998 and <i>IL-17A</i> rs8193036 polymorphisms and RA susceptibility.
|
28069745 |
2017 |
rs4711998
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results indicated that IL17A rs4711998 A/G and IL17A rs8193037 G/A polymorphisms were not associated with RA, and IL17A rs2275913 G/A and IL17A rs3819024 A/G variant alleles decrease the risk of RA, while IL17A rs3819025 G/A and IL17A rs8193036 C/T variant alleles increase the risk of RA.
|
25871515 |
2015 |
rs8193037
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results indicated that IL17A rs4711998 A/G and IL17A rs8193037 G/A polymorphisms were not associated with RA, and IL17A rs2275913 G/A and IL17A rs3819024 A/G variant alleles decrease the risk of RA, while IL17A rs3819025 G/A and IL17A rs8193036 C/T variant alleles increase the risk of RA.
|
25871515 |
2015 |
rs148704956
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggest that future larger scale studies with increased power should be performed to determine if the IL-17F 7488A/G and the IL-17A G197A polymorphisms are associated with the disease activity in patients with RA.
|
26154773 |
2015 |
rs3819025
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that IL17A rs4711998 A/G and IL17A rs8193037 G/A polymorphisms were not associated with RA, and IL17A rs2275913 G/A and IL17A rs3819024 A/G variant alleles decrease the risk of RA, while IL17A rs3819025 G/A and IL17A rs8193036 C/T variant alleles increase the risk of RA.
|
25871515 |
2015 |