Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs159153
rs159153
0.020 GeneticVariation BEFREE In this study, we investigated the association of two XRCC1 (X-ray repair cross-complementing group 1) (rs25487 and rs25489) gene polymorphisms and two OGG1 (8-oxoguanine glycosylase 1) gene polymorphisms (rs159153 and rs3219008) with the susceptibility to RA in 320 Egyptians individuals (160 RA patients and 160 controls). 26692147

2016

dbSNP: rs3219008
rs3219008
0.020 GeneticVariation BEFREE We found an association between variant XRCC1 (rs25487 and rs25489) genotype polymorphisms, OGG1 (rs3219008) genotype polymorphism, and RA disease susceptibility. 26692147

2016

dbSNP: rs159153
rs159153
0.020 GeneticVariation BEFREE We did not observe any statistically significant association of OGG1 haplotype frequencies (rs159153 and rs3219008) with RA progression. 21253737

2012

dbSNP: rs3219008
rs3219008
0.020 GeneticVariation BEFREE Our data also indicated that individuals with the AG genotype at rs</span>3219008 SNP may have a higher risk of developing RA. 21253737

2012

dbSNP: rs1052133
rs1052133
0.010 GeneticVariation BEFREE We conclude that XRCC1 Arg194Trp, and OGG1 Ser326Cys polymorphisms are not associated with RA; however, Arg399Gln polymorphism is a significant risk factor of RA, and carriers of 399Gln (G) allele have greater risk of RA. 21267572

2012

dbSNP: rs746702110
rs746702110
0.010 GeneticVariation BEFREE We conclude that XRCC1 Arg194Trp, and OGG1 Ser326Cys polymorphisms are not associated with RA; however, Arg399Gln polymorphism is a significant risk factor of RA, and carriers of 399Gln (G) allele have greater risk of RA. 21267572

2012