Gene: ABCB1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE No significant associations were found between the RFC-1/SLC19A1 (G>A [rs7499] and A>G [rs2838956]) and adenosine triphosphate-binding cassette B1 (rs1045642) gene polymorphisms and the response to MTX in RA patients. 31099054

2019
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE MDR1 3435C>T gene polymorphism influences the clinical phenotype and adverse events to MTX in the South Indian cohort of patients with RA. 26071279

2015
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE These data suggest that the presence of the MTHFR C677T and ABCB1 C3435T SNPs contribute to MTX toxicity in patients with RA. 23095111

2012
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE These results suggested that the genetic diagnosis of ABCB1 C3435T can be applied to determine MTX sensitivity for the treatment of RA patients. 17181924

2007
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE The results from the present study suggest that the 3435C>T MDR1 gene polymorphism may influence the efficacy of RA therapy with disease-modifying antirheumatic drugs. 16932953

2006