Gene: BLK ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs922483
rs922483
BLK
A 0.700 GeneticVariation GWASCAT High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. 24532676

2015
dbSNP: rs13277113
rs13277113
BLK
0.030 GeneticVariation BEFREE In summary, our results indicated that the BLK rs13277113 polymorphism was involved in the genetic background of RA in Chinese population and the association of BANK1 rs3733197 polymorphism with RA was dependent on the genotype of BLK rs13277113 polymorphism, highlighting B-cell response implicated in the pathogenesis of RA. 28925718

2017
dbSNP: rs13277113
rs13277113
BLK
0.030 GeneticVariation BEFREE In individuals carrying the BLK rs13277113 GG genotype, presence of the BANK1 rs3733197 G allele increased the risk of RA (odds ratio 1.21 [95% confidence interval 1.04-1.41], P = 0.015. 23646104

2013
dbSNP: rs13277113
rs13277113
BLK
0.030 GeneticVariation BEFREE We replicated the genetic association with rs13277113 (p = 0.0009, OR 1.46) and rs2736340 (p = 0.0001, OR 1.63) from C8orf13-BLK (8p23.1, associated with RA and systemic lupus erythematosus), and rs763361 (p = 0.03) from CD226 (18q22.3, associated with multiple sclerosis and type 1 diabetes) in the Colombian population. 21765104

2011
dbSNP: rs2248932
rs2248932
BLK
0.010 GeneticVariation BEFREE These findings suggested that the functional SNP BLK rs2248932 T/C variant allele was associated with RA development. 22740142

2012