Gene: TLR2 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5743708
rs5743708
TLR2
0.020 GeneticVariation BEFREE There was no significant association between asthma risk and rs5743708, rs3804099, and rs3804100 polymorphisms in TLR2 gene under any genetic model. 28514297

2017
dbSNP: rs5743708
rs5743708
TLR2
0.020 GeneticVariation BEFREE Our results indicated that the genotype and allele frequencies of the TLR2 Arg753Gln and TLR4 Asp299Gly polymorphisms were not significantly different between control subjects and asthmatics and were not related to in asthma features such as IgE levels, asthma history and pulmonary factors. 25530138

2015
dbSNP: rs3804099
rs3804099
TLR2
0.010 GeneticVariation BEFREE The combined results show that rs3804099 in TLR2 and rs4986791 in TLR4 were significantly associated with asthma risk. 28858111

2017
dbSNP: rs4696480
rs4696480
TLR2
0.010 GeneticVariation BEFREE Our meta-analysis reveals that the TLR2 rs4696480 polymorphism is significantly associated with asthma susceptibility, and the TLR2 rs4696480 polymorphism is a risk factor for asthma. 28514297

2017
dbSNP: rs7656411
rs7656411
TLR2
0.010 GeneticVariation BEFREE We found that patients with the TLR2/rs7656411 TT variant homozygote had a significantly reduced risk of asthma when compared with those with the GG wild-type homozygote (adjusted odds ratio [OR], 0.63; 95% confidence interval (CI], 0.41-0.98; P = .036). 20815312

2010