Gene: IL18R1 ×
Source: GWASCAT ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3771180
rs3771180
IL18R1 ; IL1RL1
T 0.820 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018
dbSNP: rs3771180
rs3771180
IL18R1 ; IL1RL1
0.820 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs10197862
rs10197862
IL18R1 ; IL1RL1
A 0.810 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013

2014
dbSNP: rs13408661
rs13408661
IL18R1 ; IL1RL1
G 0.810 GeneticVariation GWASCAT We also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus. 23028483

2012
dbSNP: rs3771166
rs3771166
IL18R1
G 0.810 GeneticVariation GWASCAT We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503

2010
dbSNP: rs9807989
rs9807989
IL18R1
0.800 GeneticVariation GWASCAT Genome-wide association study to identify genetic determinants of severe asthma. 22561531

2012
dbSNP: rs1420101
rs1420101
IL18R1 ; IL1RL1
T 0.710 GeneticVariation GWASCAT Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. 30578877

2019
dbSNP: rs1420101
rs1420101
IL18R1 ; IL1RL1
T 0.710 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018
dbSNP: rs10208293
rs10208293
IL18R1 ; IL1RL1
G 0.700 GeneticVariation GWASCAT Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. 31036433

2019
dbSNP: rs12479210
rs12479210
IL18R1 ; IL1RL1
T 0.700 GeneticVariation GWASCAT Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. 30552067

2019
dbSNP: rs1861245
rs1861245
IL18R1 ; IL1RL1
C 0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738

2019
dbSNP: rs2241116
rs2241116
IL18R1
A 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474

2019
dbSNP: rs3771175
rs3771175
IL18R1 ; IL1RL1
T 0.700 GeneticVariation GWASCAT Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. 31036433

2019
dbSNP: rs72823641
rs72823641
IL18R1 ; IL1RL1
T 0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738

2019
dbSNP: rs72823641
rs72823641
IL18R1 ; IL1RL1
T 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474

2019
dbSNP: rs72823641
rs72823641
IL18R1 ; IL1RL1
0.700 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011

2018
dbSNP: rs10208293
rs10208293
IL18R1 ; IL1RL1
G 0.700 GeneticVariation GWASCAT Identification of a new locus at 16q12 associated with time to asthma onset. 27130862

2016