Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs662
rs662
0.060 GeneticVariation BEFREE Q192R was more strongly associated with PCOS than previously suggested atherosclerosis risk markers. 30900463

2019

dbSNP: rs662
rs662
0.060 GeneticVariation BEFREE The Q192R (rs662; A/G) polymorphism, which results in the glutamine to arginine substitution at position 192, of the PON1 gene has been linked to increased atherosclerosis risk in several but not all population studies. 23625196

2013

dbSNP: rs662
rs662
0.060 GeneticVariation BEFREE Serum PON-1 activity but not Q192R polymorphism is related to the extent of atherosclerosis. 22188760

2012

dbSNP: rs662
rs662
0.060 GeneticVariation BEFREE Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study. 21982484

2011

dbSNP: rs662
rs662
0.060 GeneticVariation BEFREE In this study, we enrolled 1746 type 2 diabetic subjects, determined 4 common genetic variants related to oxidative stress (glutamate-cysteine ligase modifier subunit (GCLM) C-588T, myeloperoxidase G-463A, human paraoxonase 1 Gln192Arg and NAD(P)H oxidase p22phox C242T polymorphisms), and measured carotid intima-media thickness (IMT) as a surrogate marker for atherosclerosis. 19126404

2009

dbSNP: rs662
rs662
0.060 GeneticVariation BEFREE In logistic regression analysis, age (P<0.001) and the PON M/L55 genotype (P=0.015) were associated significantly with the severity of atherosclerosis in the common iliac arteries independent of smoking status, R/Q192 genotype, hypertension, diabetes mellitus, BMI and sex. 11472729

2001

dbSNP: rs854560
rs854560
0.050 GeneticVariation BEFREE Association of paraoxonase-1 L55M and Q192R polymorphisms with PCOS risk and potential risk factors for atherosclerosis. 30900463

2019

dbSNP: rs854560
rs854560
0.050 GeneticVariation BEFREE The polymorphisms of ApoE and paraoxonase (PON1) L55M (Met < Leu) allele genes lead to disorders in lipid metabolism and are related to atherosclerosis. 29273831

2018

dbSNP: rs854560
rs854560
0.050 GeneticVariation BEFREE We related the PON1 M55L genotypes to the extent of atherosclerosis in left anterior descending coronary artery (LAD) in alcohol abstainers (0-1 g of alcohol/day), moderate consumers (1-36 g of alcohol/day) and drinkers (> 36 g of alcohol/day). 15284530

2004

dbSNP: rs854560
rs854560
0.050 GeneticVariation BEFREE We studied the association of the PON1 M/L55 genotype with the extent of atherosclerosis in an autopsy series of Finnish males. 14642403

2003

dbSNP: rs854560
rs854560
0.050 GeneticVariation BEFREE In logistic regression analysis, age (P<0.001) and the PON M/L55 genotype (P=0.015) were associated significantly with the severity of atherosclerosis in the common iliac arteries independent of smoking status, R/Q192 genotype, hypertension, diabetes mellitus, BMI and sex. 11472729

2001