|
rs6790396
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
|
30061737 |
2018 |
|
rs6790396
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Multi-ethnic genome-wide association study for atrial fibrillation.
|
29892015 |
2018 |
|
rs6795970
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There was a significant difference in the allele distribution (p = 7.86 × 10<sup>-5</sup>) and genotype distribution (p = 1.42 × 10<sup>-5</sup>) of rs6795970 between the AF recurrence and no recurrence groups.
|
28281580 |
2017 |
|
rs6800541
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The nonsynonymous SCN10A single nucleotide polymorphism (SNP) rs6795970 has been reported to associate with PR interval and atrial fibrillation (AF) and in strong linkage disequilibrium (LD) with the AF-associated SNP rs6800541.
|
28281580 |
2017 |
|
rs6800541
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genome-wide association studies have shown that the common single nucleotide polymorphism rs6800541 located in SCN10A, encoding the voltage-gated Nav1.8 sodium channel, is associated with PR-interval prolongation and atrial fibrillation (AF).
|
25691686 |
2015 |
|
rs6795970
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The common variant rs6795970 in SCN10A is associated with the PR interval duration among healthy patients and those with AF.
|
24072447 |
2014 |
|
rs6771157
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression analysis in an additive genetic model revealed that one SNP in SCN10A (rs6771157</span>) was associated with an increased risk of AF (adjusted OR = 1.20, 95% CI: 1.06 - 1.36, P = 0.003).
|
27725708 |
2016 |
|
rs10428132
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this meta-analysis, both rs10428132 at SCN10A (OR=0.73, P=5.7 × 10(-6)) and rs11708996 at SCN5A (OR=0.80, P=0.02) showed a statistically significant decreased risk of AF.
|
24667784 |
2014 |
|
rs12632942
|
|
|
0.010 |
GeneticVariation |
BEFREE |
On unadjusted analysis, heart rate response during AF was associated with rs6795970 (P = 0.035, partial R(2) = 0.015), but not with rs12632942 (P = 0.89), and neither association was significant after adjustment for covariates.
|
24072447 |
2014 |