| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
T | 0.700 | GeneticVariation | GWASCAT | Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. | 30261039 | 2018 |
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|
C | 0.700 | GeneticVariation | GWASCAT | Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. | 30261039 | 2018 |
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|
G | 0.700 | GeneticVariation | GWASCAT | Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. | 30261039 | 2018 |
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|
T | 0.700 | GeneticVariation | GWASCAT | Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. | 30261039 | 2018 |
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|
GA | 0.700 | CausalMutation | CLINVAR | ||||||
|
C | 0.700 | CausalMutation | CLINVAR | ||||||
|
A | 0.700 | CausalMutation | CLINVAR | ||||||
|
0.010 | GeneticVariation | BEFREE | C282Y homozygote women (n = 312, 0.7%) aged 65-70 were more likely to be frail (OR 1.73: 1.05-2.84, p = .032) and have chronic knee, hip, and back pain. | 30657865 | 2019 |
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|
0.010 | GeneticVariation | BEFREE | A significantly higher preoperative back pain intensity was observed among rs6746030 A minor allele carriers, compared with GG homozygotes (VAS = 7.5 ± 2.4 vs 6.5 ± 2.7, P = 0.012). | 29106681 | 2018 |
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|
0.010 | GeneticVariation | BEFREE | Single marker analysis revealed 1 SNP (rs998259; minor allele T) that was significantly associated with improvement in both absolute ODI score (P = 0.030) and Numerical Rating Scale back pain scores (P = 0.033) following surgery. | 20838263 | 2010 |