rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, considering that these parameters are determinant for protein interactions and, consequently, protein function; the alterations observed throughout the MD analyses may be related to the functional impairment of BDNF upon V66M mutation, as well as its involvement in psychiatric disorders.
|
30998730 |
2019 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, considering that these parameters are determinant for protein interactions and, consequently, protein function; the alterations observed throughout the MD analyses may be related to the functional impairment of BDNF upon V66M mutation, as well as its involvement in psychiatric disorders.
|
30998730 |
2019 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study provides evidence that Val66Met is associated with cortical maturation in children and adolescents with and without psychiatric disorders.
|
29288952 |
2018 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
While the BDNF Val66Met polymorphism has been linked to various psychological disorders, limited focus has been on its relationship to posttraumatic stress disorder (PTSD) and early traumas such as child abuse.
|
29649711 |
2018 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
While the BDNF Val66Met polymorphism has been linked to various psychological disorders, limited focus has been on its relationship to posttraumatic stress disorder (PTSD) and early traumas such as child abuse.
|
29649711 |
2018 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study provides evidence that Val66Met is associated with cortical maturation in children and adolescents with and without psychiatric disorders.
|
29288952 |
2018 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) is associated with psychiatric disorders and regional gray matter volume (rGMV) in adults.
|
26830347 |
2016 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) is associated with psychiatric disorders and regional gray matter volume (rGMV) in adults.
|
26830347 |
2016 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Variants in BDNF, in particular the functional Val66Met polymorphism (rs6265), have been found to be associated with a number of psychiatric disorders, cognitive function, and obesity.
|
24708359 |
2015 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Val66Met (also known as rs6265 or G196A), the only known functional polymorphism of the BDNF gene, has been widely studied and considered to be associated with risk of some psychiatric disorders such as bipolar disorder and schizophrenia.
|
26503495 |
2015 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Here we comprehensively review the role and relevance of the Val66Met polymorphism in psychiatric disorders, with emphasis on suicidal behavior and anxiety, eating, mood and psychotic disorders.
|
25824305 |
2015 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Val66Met (also known as rs6265 or G196A), the only known functional polymorphism of the BDNF gene, has been widely studied and considered to be associated with risk of some psychiatric disorders such as bipolar disorder and schizophrenia.
|
26503495 |
2015 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Here we comprehensively review the role and relevance of the Val66Met polymorphism in psychiatric disorders, with emphasis on suicidal behavior and anxiety, eating, mood and psychotic disorders.
|
25824305 |
2015 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Variants in BDNF, in particular the functional Val66Met polymorphism (rs6265), have been found to be associated with a number of psychiatric disorders, cognitive function, and obesity.
|
24708359 |
2015 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Using clinical data and DNA samples from mouthwash gathered from an epidemiological study on the prevalence of mental disorders in youths between 12 and 17 years old, we tested the statistical interaction between a set of psychosocial adversities experienced during childhood (CAs) with two common polymorphisms in the brain-derived neurotrophic factor (BDNF) (Val66Met) and SLC6A4 (L/S) genes on the probability of suffering MDD in adolescence.
|
24683520 |
2014 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Using clinical data and DNA samples from mouthwash gathered from an epidemiological study on the prevalence of mental disorders in youths between 12 and 17 years old, we tested the statistical interaction between a set of psychosocial adversities experienced during childhood (CAs) with two common polymorphisms in the brain-derived neurotrophic factor (BDNF) (Val66Met) and SLC6A4 (L/S) genes on the probability of suffering MDD in adolescence.
|
24683520 |
2014 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent studies show that the Val(66)Met BDNF polymorphism correlates with various psychiatric disorders, including anxiety, but there are several differences between experimental and clinical studies.
|
24051499 |
2013 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent studies show that the Val(66)Met BDNF polymorphism correlates with various psychiatric disorders, including anxiety, but there are several differences between experimental and clinical studies.
|
24051499 |
2013 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (val66met) in the brain derived neurotrophic factor (BDNF) gene has been shown to be a risk factor for a number of psychiatric disorders, including schizophrenia.
|
20957650 |
2010 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In spite of abundant evidence that Val66Met BDNF polymorphism has an impact on several different neurological or psychiatric disorders, we conclude that a major clinical impact of Val66Met polymorphism as a disease modifier in temporal lobe epilepsy is probably unlikely.
|
19896331 |
2010 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
G196A, a common polymorphism of the BDNF gene, not only affects cognitive and motor processes, but also is associated with various psychiatric disorders.
|
20085561 |
2010 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Several polymorphisms in BDNF have been reported and studied in psychiatric disorders but the most frequent is the p.Val66Met (rs6265G > A) single nucleotide polymorphism (SNP), with functional effects on the intracellular trafficking and secretion of the protein.
|
19603419 |
2010 |
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Several polymorphisms in BDNF have been reported and studied in psychiatric disorders but the most frequent is the p.Val66Met (rs6265G > A) single nucleotide polymorphism (SNP), with functional effects on the intracellular trafficking and secretion of the protein.
|
19603419 |
2010 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (val66met) in the brain derived neurotrophic factor (BDNF) gene has been shown to be a risk factor for a number of psychiatric disorders, including schizophrenia.
|
20957650 |
2010 |
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In spite of abundant evidence that Val66Met BDNF polymorphism has an impact on several different neurological or psychiatric disorders, we conclude that a major clinical impact of Val66Met polymorphism as a disease modifier in temporal lobe epilepsy is probably unlikely.
|
19896331 |
2010 |