Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17095355
rs17095355
ADD3-AS1
0.840 GeneticVariation BEFREE The risk allele frequencies of rs2501577, rs11194981, and rs17095355 in the BA group were significantly higher than in the controls. 29508064

2018
dbSNP: rs17095355
rs17095355
ADD3-AS1
0.840 GeneticVariation BEFREE Two SNPs in <i>ADD3</i> were replicated as associated with BA (1.60E-04 ≤ <i>P</i>≤1.70E-04, 1.33 ≤ odds ratio (OR) ≤ 1.58 for rs17095355, 2.10E-04 ≤ <i>P</i>≤5.30E-04, 1.26 ≤ OR ≤ 1.57 for rs2501577). 29685956

2018
dbSNP: rs17095355
rs17095355
ADD3-AS1
0.840 GeneticVariation BEFREE This meta-analysis confirms the association of rs17095355 polymorphism and BA development, especially in Asians. 27557278

2017
dbSNP: rs17095355
rs17095355
ADD3-AS1
0.840 GeneticVariation BEFREE This study suggests that the ADD3 gene plays an important role in BA pathogenesis and reveals a significant association between two SNPs, rs17095355 and rs10509906, and BA. 25285724

2014
dbSNP: rs17095355
rs17095355
ADD3-AS1
T 0.840 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs17095355
rs17095355
ADD3-AS1
T 0.840 GeneticVariation GWASCAT Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs6761893
rs6761893
EFEMP1
T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1. 30102696

2018
dbSNP: rs11101722
rs11101722 		0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs13198304
rs13198304
LY86-AS1
0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs17139085
rs17139085
RBFOX1
0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs2510389
rs2510389 		0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs3755256
rs3755256
HPCAL1
0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs3813280
rs3813280
FRG1-DT
0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs4869544
rs4869544
WDR70 ; RNU6-484P
0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs6843588
rs6843588
CBR4
0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs6966038
rs6966038 		0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs952178
rs952178
LINC02492 ; LOC105377604
0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs9612574
rs9612574 		0.700 GeneticVariation GWASDB Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. 20460270

2010
dbSNP: rs113624356
rs113624356
BBS1 ; ZDHHC24
G 0.700 CausalMutation CLINVAR

dbSNP: rs10509906
rs10509906
ADD3 ; ADD3-AS1
0.020 GeneticVariation BEFREE Though we failed to replicate the individual association of rs10509906 to disease, the intragenic epistatic effect between rs10509906 and rs2501577 was suggested as exhibiting susceptibility to BA, further cross-validated by multifactor dimensionality reduction (MDR) (<i>P</i>=0.068, OR = 1.37), which may explain extra hidden heritability of <i>ADD3</i> to BA. 29685956

2018
dbSNP: rs2501577
rs2501577
ADD3
0.020 GeneticVariation BEFREE Two SNPs in <i>ADD3</i> were replicated as associated with BA (1.60E-04 ≤ <i>P</i>≤1.70E-04, 1.33 ≤ odds ratio (OR) ≤ 1.58 for rs17095355, 2.10E-04 ≤ <i>P</i>≤5.30E-04, 1.26 ≤ OR ≤ 1.57 for rs2501577</span>). 29685956

2018
dbSNP: rs2501577
rs2501577
ADD3
0.020 GeneticVariation BEFREE SNP-SNP interaction analysis showed that the SNP combination of the two genes rs17095355 and rs2501577 provided an additive increase in BA risk. 29508064

2018
dbSNP: rs10509906
rs10509906
ADD3 ; ADD3-AS1
0.020 GeneticVariation BEFREE This study suggests that the ADD3 gene plays an important role in BA pathogenesis and reveals a significant association between two SNPs, rs17095355 and rs10509906, and BA. 25285724

2014
dbSNP: rs187238
rs187238
IL18
0.010 GeneticVariation BEFREE Interestingly, we also observed that the intragenic synergistic epistasis between SNPs rs187238 and rs1946518 boosting the risk to BA by logistic regression and Multifactor dimensionality reduction (MDR) analysis. 30059753

2018
dbSNP: rs1946518
rs1946518
IL18
0.010 GeneticVariation BEFREE Interestingly, we also observed that the intragenic synergistic epistasis between SNPs rs187238 and rs1946518 boosting the risk to BA by logistic regression and Multifactor dimensionality reduction (MDR) analysis. 30059753

2018