Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs118203347
rs118203347
0.700 GeneticVariation UNIPROT

dbSNP: rs118203385
rs118203385
0.700 GeneticVariation UNIPROT

dbSNP: rs1323541164
rs1323541164
0.700 GeneticVariation UNIPROT

dbSNP: rs1695
rs1695
0.070 GeneticVariation BEFREE We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population. 11757669

2001

dbSNP: rs768623239
rs768623239
0.020 GeneticVariation BEFREE We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population. 11757669

2001

dbSNP: rs2066853
rs2066853
AHR
0.010 GeneticVariation BEFREE To assess two polymorphic forms of aryl hydrocarbon receptor (AHR) gene, G1721A (R554K), and G1768A (V570I) in Chinese population and to explore the possible association of human AHR gene polymorphism with elevated incidence of bladder cancer among Chinese Han subjects in east of China. 11866883

2002

dbSNP: rs4986826
rs4986826
AHR
0.010 GeneticVariation BEFREE To assess two polymorphic forms of aryl hydrocarbon receptor (AHR) gene, G1721A (R554K), and G1768A (V570I) in Chinese population and to explore the possible association of human AHR gene polymorphism with elevated incidence of bladder cancer among Chinese Han subjects in east of China. 11866883

2002

dbSNP: rs1042028
rs1042028
0.040 GeneticVariation BEFREE Because of its functional role and published data showing the influence of Arg213His polymorphism on the risk of some cancers, we hypothesized that the His(213) allele of the SULT1A1 gene may modify bladder cancer risk. 14643027

2003

dbSNP: rs9282861
rs9282861
0.040 GeneticVariation BEFREE Because of its functional role and published data showing the influence of Arg213His polymorphism on the risk of some cancers, we hypothesized that the His(213) allele of the SULT1A1 gene may modify bladder cancer risk. 14643027

2003

dbSNP: rs25487
rs25487
0.100 GeneticVariation BEFREE Our data are consistent with a potential role of the XRCC1 Arg399Gln polymorphism in bladder cancer susceptibility and further suggest that there may be DNA lesions important in bladder carcinogenesis, repaired by the base excision repair mechanism, that are not directly associated with tobacco smoking. 15298955

2004

dbSNP: rs1043210477
rs1043210477
0.020 GeneticVariation BEFREE The GPX1 Pro/Leu genotype may significantly increase the risk of bladder cancer and the increased risk may be modified by the Ala-9Val MnSOD polymorphism. 15247771

2004

dbSNP: rs1805087
rs1805087
MTR
0.020 GeneticVariation BEFREE We investigated joint effects of polymorphisms of the MTHFR (677 C-->T, 1298A-->C) and MS genes (2756 A-->G), dietary folate intake and cigarette smoking on the risk of bladder cancer in a case-control study. 15117811

2004

dbSNP: rs953038635
rs953038635
0.020 GeneticVariation BEFREE The GPX1 Pro/Leu genotype may significantly increase the risk of bladder cancer and the increased risk may be modified by the Ala-9Val MnSOD polymorphism. 15247771

2004

dbSNP: rs121909218
rs121909218
0.010 GeneticVariation BEFREE To address these issues, we stably transfected several commonly used human bladder cancer cell lines with known invasive phenotypes with either wild-type PTEN constructs or those deficient in the lipid phosphatase (G129E) or both protein and lipid phosphatase (G129R) activities. 15273733

2004

dbSNP: rs2074647
rs2074647
0.010 GeneticVariation BEFREE When the SNPs were analyzed separately, the RGS6-rs2074647 (C-->T) polymorphism conferred the greatest overall reduction in risk of bladder cancer (odds ratio, 0.66; 95% confidence interval, 0.46-0.95). 15375002

2004

dbSNP: rs786204929
rs786204929
0.010 GeneticVariation BEFREE To address these issues, we stably transfected several commonly used human bladder cancer cell lines with known invasive phenotypes with either wild-type PTEN constructs or those deficient in the lipid phosphatase (G129E) or both protein and lipid phosphatase (G129R) activities. 15273733

2004

dbSNP: rs1217691063
rs1217691063
0.090 GeneticVariation BEFREE To clarify the role of MTHFR polymorphisms on bladder cancer risk, we genotyped MTHFR 677C > T and MTHFR 1298A > C in a population-based study of bladder cancer of 352 patients and 551 controls from New Hampshire, USA. 16217917

2005

dbSNP: rs2228001
rs2228001
XPC
0.090 GeneticVariation BEFREE Using logistic regression adjusting for smoking, occupational and family history, neither the heterozygote nor the homozygote variants of these polymorphisms were associated with increased bladder cancer risk (adjusted odds ratio [95% confidence interval] for heterozygote 0.82 [0.63-1.07], 0.82 [0.63-1.08] and 0.83 [0.63-1.08] for PolyAT, IVS11-6 and Lys939Gln, respectively and homozygote variant, 0.98 [0.68-1.42], 0.99 [0.69-1.43] and 1.01 [0.70-1.46]). 15886698

2005

dbSNP: rs397507444
rs397507444
0.080 GeneticVariation BEFREE To clarify the role of MTHFR polymorphisms on bladder cancer risk, we genotyped MTHFR 677C > T and MTHFR 1298A > C in a population-based study of bladder cancer of 352 patients and 551 controls from New Hampshire, USA. 16217917

2005

dbSNP: rs386675647
rs386675647
0.020 GeneticVariation BEFREE An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. 15615884

2005

dbSNP: rs7439366
rs7439366
0.020 GeneticVariation BEFREE An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. 15615884

2005

dbSNP: rs758272654
rs758272654
0.020 GeneticVariation BEFREE We have recently shown an association between the GNAS1 T393C polymorphism and disease progression in patients with bladder cancer with homozygous TT genotypes displaying increased transcription of Galpha s and a more favorable clinical course compared with C-allele carriers. 16033819

2005

dbSNP: rs758272654
rs758272654
0.020 GeneticVariation BEFREE The T393C polymorphism of the G alpha s gene (GNAS1) is a novel prognostic marker in bladder cancer. 15824158

2005

dbSNP: rs765502022
rs765502022
0.020 GeneticVariation BEFREE An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. 15615884

2005

dbSNP: rs1041983
rs1041983
0.010 GeneticVariation BEFREE To investigate whether the slow acetylator genotype is a risk factor for development of bladder cancer following schistosomal infection of the urinary tract, the authors determined the frequencies of 3 common polymorphisms in the NAT2 gene (341T>C, 590G>A, and 282C>T), which are associated with impaired acetylation activity, in control subjects (n=61; mean age 34.3+/-9.2 years) and in schistosomiasis-associated bladder cancer patients (n=55; 52+/-10.9 years) from the Egyptian population. 15905799

2005