|
rs113507694
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.
|
28632202 |
2017 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Amygdala responses across genotypes (Val66Met SNP Met allele-carriers vs. Non-Met carriers) and diagnoses (HC, BPD, SPD) were examined with ANOVA.
|
28371657 |
2017 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Amygdala responses across genotypes (Val66Met SNP Met allele-carriers vs. Non-Met carriers) and diagnoses (HC, BPD, SPD) were examined with ANOVA.
|
28371657 |
2017 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The positive association of BNDF Val66Met with high BMI values replicates previous findings in patients with SCZ and indicates the BDNF Val66Met genotype as a potential risk factor for obesity and insulin resistance measures in patients with BPD receiving antipsychotics as well.
|
25874530 |
2015 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The positive association of BNDF Val66Met with high BMI values replicates previous findings in patients with SCZ and indicates the BDNF Val66Met genotype as a potential risk factor for obesity and insulin resistance measures in patients with BPD receiving antipsychotics as well.
|
25874530 |
2015 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Overall, there was no significant difference in allelic distribution of Val66Met polymorphism between patients and controls with a pooled OR = 1.03 (95% CI 0.98, 1.08) although there was a trend towards association between Val66Met polymorphism and BPD in Caucasians with an OR of 1.08 (95% CI 1.00, 1.16).
|
25539739 |
2014 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Overall, there was no significant difference in allelic distribution of Val66Met polymorphism between patients and controls with a pooled OR = 1.03 (95% CI 0.98, 1.08) although there was a trend towards association between Val66Met polymorphism and BPD in Caucasians with an OR of 1.08 (95% CI 1.00, 1.16).
|
25539739 |
2014 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The association between Val66Met polymorphism and BPD, treatment response to mood stabilizers, was estimated.
|
22548711 |
2012 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The association between Val66Met polymorphism and BPD, treatment response to mood stabilizers, was estimated.
|
22548711 |
2012 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The interrelations between serious life events, impulsive aggression and the BDNF Val(66)Met polymorphism as well as their implication for BPD are far from understood and require further investigations.
|
19817874 |
2010 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Previous studies have suggested that the Val66Met (also known as rs6265 or G196A) variant of BDNF is associated with bipolar disorder (BPD), but the results have been inconclusive.
|
19330778 |
2010 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The interrelations between serious life events, impulsive aggression and the BDNF Val(66)Met polymorphism as well as their implication for BPD are far from understood and require further investigations.
|
19817874 |
2010 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Previous studies have suggested that the Val66Met (also known as rs6265 or G196A) variant of BDNF is associated with bipolar disorder (BPD), but the results have been inconclusive.
|
19330778 |
2010 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The study demonstrates that the BDNF C-270T and Val66Met polymorphisms are unlikely to contribute to the genetic predisposition to BPD as a whole.
|
18242852 |
2008 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The study demonstrates that the BDNF C-270T and Val66Met polymorphisms are unlikely to contribute to the genetic predisposition to BPD as a whole.
|
18242852 |
2008 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Two family-based association studies showed that the Val allele of the functional polymorphism Val66Met in the BDNF gene is associated with BPD; however, others could not confirm the results.
|
16152572 |
2005 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Two family-based association studies showed that the Val allele of the functional polymorphism Val66Met in the BDNF gene is associated with BPD; however, others could not confirm the results.
|
16152572 |
2005 |
|
rs6265
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no evidence for an allelic or genotypic association of two polymorphisms (-1360C>T and 196G>A) of the BDNF gene with BPD.
|
12524161 |
2003 |
|
rs759834365
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no evidence for an allelic or genotypic association of two polymorphisms (-1360C>T and 196G>A) of the BDNF gene with BPD.
|
12524161 |
2003 |
|
rs25531
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SLC6A4 polymorphisms are not associated with the risk of developing major psychiatric disorders (SCZ and BPD); however some signals were detected in ALC (HTTLPR p<sub>d</sub> = 9.25 × 10<sup>-03</sup>, p<sub>r</sub> = 7.24 × 10<sup>-03</sup>; rs2066713 p<sub>d</sub> = 6.35 × 10<sup>-08</sup>; rs25531 p<sub>d</sub> = 2.95 × 10<sup>-02</sup>; rs4251417 p<sub>d</sub> = 2.46 × 10<sup>-03</sup>), and ALZ (rs6354 p<sub>r</sub> = 1.22 × 10<sup>-02</sup>; rs7224199 p<sub>d</sub> = 1.00 × 10<sup>-08</sup>, p<sub>r</sub> = 2.65 × 10<sup>-02</sup>) cohorts.
|
31595439 |
2020 |
|
rs53576
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In particular, rs53576 and rs2254298 were found to be significantly involved in gene-environment interactions that modulated risk for psychopathology and the following psychiatric disorders: disruptive behavior, depression, anxiety, eating disorder and borderline personality disorder.
|
29033100 |
2018 |
|
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Meta-analysis showed that MTHFR C677T was significantly associated with SZ, the highest OR was found for the recessive model (for TT vs. CT + CC: OR = 1.34, 95% CI: 1.18-1.53); a marginal association of MTHFR C677T with increased risk of BPD has also been found for the recessive model (OR = 1.26, 95% CI: 1.00-1.59).
|
24938371 |
2015 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Subgroup analysis indicated a significant association with SZ existed in Asian populations, not among the white populations and no significant association was detected between the MTHFR A1298C and BPD in all groups.
|
24938371 |
2015 |
|
rs53576
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We examined whether a polymorphism of the oxytocin receptor gene (OXTR rs53576) interacts with quality of family functioning to predict borderline personality disorder (BPD) symptomatology in a sample of youth at age 20.
|
25102084 |
2015 |
|
rs10994336
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Following stratification by ethnicity, variants of the ANK3 gene (rs1938516 and rs10994336) were found to be associated with BPD in Malays (P-value=0.001 and 0.006, respectively).
|
24914473 |
2014 |