|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have also evaluated a Val(655)Ile single nucleotide polymorphism, which is associated with an increased risk of breast cancer, in a subset of the colorectal cancer patients and in healthy control subjects.
|
11870539 |
2002 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recent studies indicated an association between the Ile to Val polymorphism at codon 655 of HER-2 and susceptibility to breast cancer.
|
11857355 |
2002 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this case control study we aimed to analyze the frequency of HER1 R497K (rs 11543848) and HER2 I655V (rs 1136201) Polymorphisms in breast cancer.
|
23594562 |
2013 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
HER2 Ile655Val polymorphism is negatively associated with breast cancer susceptibility.
|
29417620 |
2018 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A case (n=250)-control (n=500) study was undertaken to investigate the role of Single Nucleotide Polymorphisms (SNP's) in GSTM1 (Present/Null); GSTP1 (Ile105Val), p53 (Arg72Pro), TGFbeta1 (Leu10Pro), c-erbB2 (Ile655Val), and GSTT1 (Null/Present) in breast cancer.
|
18058229 |
2008 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In our study, we analyzed three polymorphisms in the HER2 gene: the single-nucleotide polymorphism (SNP) HER2 Ile(655)Val as well as another SNP (rs903506) close to it and a new screened dinucleotide repeat H(AC)I4 in intron 4, in a sample of 148 cases and 290 controls from the Tunisian population and investigated their association with breast cancer risk.
|
19929405 |
2010 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The association of HER-2/neu Ile655Val polymorphism and the risk of breast cancer was borderline significant with the heterozygous carrier being at higher risk.
|
18837888 |
2008 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A case-control study of the HER2 Ile655Val polymorphism and risk of breast cancer in Taiwan.
|
18062925 |
2008 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This meta-analysis aimed to assess the association between ERBB2 Ile655Val and Ala1170Pro polymorphisms and the susceptibility to breast cancer.
|
23900832 |
2013 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Animal studies and protein modeling suggest that the Ile655Val polymorphism located in the transmembrane domain of the HER2 protein might influence breast cancer development by altering the efficiency of homodimerization.
|
15987431 |
2005 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Analysis on clinico-pathological parameters showed neither HER2 Ile655Val nor PTEN IVS4 genotypes were not associated with any of the variables (p > 0.05).In conclusion, our findings suggest that the Ile/Val genotype of HER2 and ATCTT insertion (+/+) genotype of PTEN IVS4 gene may play an important role as genetic markers for breast cancer risk, but both genes genotypes may not be useful for predicting tumor prognosis in Turkish population.
|
23086302 |
2013 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphisms of HER2 Ile655Val and cyclin D1 (CCND1) G870A are not associated with breast cancer risk but polymorphic allele of HER2 is associated with nodal metastases.
|
18237245 |
2008 |
|
rs1136201
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study was conducted to clarify the predictive and prognostic significance of serum TGF-I(2)1 in breast cancer in relation to Ile655Val single nucleotide polymorphism (SNP) of human epidermal growth factor receptor-2 (HER-2).
|
18348656 |
2008 |