rs2279115
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Simultaneously, rs2279115 was correlated with a significantly higher risk of cancer prognosis in Asia but not in Caucasian.
|
28445963 |
2017 |
rs2279115
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A functional single-nucleotide polymorphism (c.-938C>A, rs2279115) in the inhibitory P2 BCL2 gene promoter has been associated with clinical outcomes in various types of cancer.
|
28396899 |
2017 |
rs2279115
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Our results indicate that the BCL-2 rs2279115 genetic variant was associated with SCLC risk in Chinese populations and support the hypothesis that SNPs in regulatory regions of oncogenes might contribute to cancer susceptibility.
|
26311051 |
2016 |
rs2279115
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Multiple functional BCL-2 genetic polymorphisms, such as rs2279115, rs1801018 and rs1564483, have been identified previously and might be involved in cancer development through deregulating BCL-2 expression.
|
26132559 |
2015 |
rs2279115
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A regulatory (-938C>A, rs2279115) single-nucleotide polymorphism in the inhibitory P2 BCL-2 gene promoter generates significantly different BCL-2 promoter activities and has been associated with different clinical outcomes in various malignancies.
|
25257838 |
2015 |
rs2279115
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This meta-analysis was performed to evaluate the relationships of Bcl-2 -938 C>A polymorphism (rs2279115) with susceptibility and prognosis of cancer.
|
25430556 |
2014 |
rs1801018
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results showed statistically significant association between rs2279115 and cancer susceptibility and prognosis in all four genetic models but not in rs1801018.
|
28445963 |
2017 |
rs1564483
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple functional BCL-2 genetic polymorphisms, such as rs2279115, rs1801018 and rs1564483, have been identified previously and might be involved in cancer development through deregulating BCL-2 expression.
|
26132559 |
2015 |
rs780634396
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Recently, the E17K mutation in the AKT1 has been associated with multiple human malignancies and leukemia in mice.
|
20440266 |
2010 |