|
rs1019238
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study of DSM-IV cannabis dependence.
|
21668797 |
2011 |
|
rs12491921
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study of DSM-IV cannabis dependence.
|
21668797 |
2011 |
|
rs1431318
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study of DSM-IV cannabis dependence.
|
21668797 |
2011 |
|
rs806380
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Two SNPs that were previously associated with cannabis dependence in other studies were also significant with this phenotype in our analyses [rs806368 (P = 0.05) and rs806380 (P = 0.009)].
|
19016476 |
2009 |
|
rs806380
|
|
|
0.030 |
GeneticVariation |
BEFREE |
These results provide inconclusive evidence of association between rs1049353/rs806380 and the development of cannabis dependence, and underscore the importance of replicating results of genetic association studies.
|
19443135 |
2009 |
|
rs806380
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Univariate (single-marker) association tests demonstrated that SNP rs806380, located in intron 2 of the CNR1 gene, was significantly associated with developing one or more cannabis dependence symptoms, with the G allele having a protective effect (P < 0.02).
|
16917946 |
2006 |
|
rs1049353
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, we discuss the interaction between the 1359 G/A polymorphism of the CNR1 gene and the DRD2 gene polymorphisms and the net effect of any possible epistasis on the cannabis addiction phenotype in a Turkish population.
|
26833047 |
2016 |
|
rs2609997
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In the current imaging genetics study, we investigated a single nucleotide polymorphism (SNP) of the protein-coding proenkephalin gene (PENK: rs2609997, recently shown to be associated with cannabis dependence) in 55 individuals with cocaine use disorder and 37 healthy controls.
|
26164485 |
2015 |
|
rs2609997
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Moreover, PENK variants (rs2576573 and rs2609997) significantly related to Neuroticism and cannabis dependence.
|
22745721 |
2012 |
|
rs1049353
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Case-control analysis identified a nominal association between SNP rs1049353 and having one or more cannabis dependence symptoms (p=.029), but the association did not hold up in a combined sample.
|
19443135 |
2009 |
|
rs604300
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis.
|
26595473 |
2015 |
|
rs17664708
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the association analysis of the Study of Addiction: Genetics and Environment sample under the linkage peak, we identified one SNP (rs17664708) associated with CaD in both AAs (odds ratio [OR] = 2.93, p = .0022) and European Americans (OR = 1.38, p = .02).
|
22520967 |
2012 |
|
rs2023239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism in the cannabis receptor-1 gene (CNR1), rs2023239, has been associated with CD diagnosis and intermediate phenotypes, including abstinence-induced withdrawal, cue-elicited craving, and parahippocampal activation to cannabis cues.
|
22669173 |
2012 |
|
rs2576573
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, PENK variants (rs2576573 and rs2609997) significantly related to Neuroticism and cannabis dependence.
|
22745721 |
2012 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple logistic regression analysis of the C3435T SNP and variables identified in univariate analyses indicated that the CC genotype was independently associated with cannabis dependence (P=0.045, OR=6.61 [1.05-46.58]).
|
19625010 |
2009 |
|
rs806368
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNPs that were previously associated with cannabis dependence in other studies were also significant with this phenotype in our analyses [rs806368 (P = 0.05) and rs806380 (P = 0.009)].
|
19016476 |
2009 |
|
rs7162140
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriers of the rs7162140 T-allele were also found to have nearly a 3-fold increased risk of developing cannabis dependence (OR=2.9 (95%CI 1.1-7.4); p=0.03).
|
17608938 |
2007 |