Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
---|---|---|---|---|---|---|---|---|---|---|
|
0.040 | GeneticVariation | BEFREE | Subgroup analysis showed that rs2279744 (SNP309) was associated with the risk of gynecological cancers in Caucasian and Asian according to the ethnicity and cancer type, especially for endometrial cancer. | 29480845 | 2018 |
||||
|
0.040 | GeneticVariation | BEFREE | In conclusion, the study found that MDM2 rs2279744 polymorphism was significantly associated with endometrial cancer risk in a Chinese Han population. | 29096752 | 2017 |
||||
|
0.040 | GeneticVariation | BEFREE | The aim of the study was to determine an association of TP53 codon 72 (Arg72Pro, G>C transversion, rs1042522) and MDM2 SNP309 (T>G change, rs2279744) polymorphisms in endometrial cancer (EC) of postmenopausal women, regarding grading and staging of EC. | 25316267 | 2014 |
||||
|
0.040 | GeneticVariation | BEFREE | Our pooled data suggest evidence for a major role of MDM2 rs2279744 polymorphism in the carcinogenesis of endometrial cancer, especially among Caucasian populations. | 24293392 | 2014 |
||||
|
0.020 | GeneticVariation | BEFREE | The aim of the study was to determine an association of TP53 codon 72 (Arg72Pro, G>C transversion, rs1042522) and MDM2 SNP309 (T>G change, rs2279744) polymorphisms in endometrial cancer (EC) of postmenopausal women, regarding grading and staging of EC. | 25316267 | 2014 |
||||
|
0.020 | GeneticVariation | BEFREE | Association of MDM2 SNP309 and TP53 Arg72Pro polymorphisms with risk of endometrial cancer. | 23624782 | 2013 |
||||
|
0.010 | GeneticVariation | BEFREE | Increasing evidence has suggested that rs2279744 is associated with rs117039649 polymorphism, which can increase the risk of gynecological cancers, including cervical, ovarian, breast, and endometrial cancer. | 29480845 | 2018 |