|
rs4994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of a subgroup with a higher body mass index showed that the Trp64Arg variant increased the OR (2.63; 95% confidence interval, 1.13-6.11) for colon cancer, but not for rectal cancer, compared with the Trp64 genotype.
|
11706779 |
2001 |
|
rs671
|
|
|
0.020 |
GeneticVariation |
BEFREE |
However, with the rectal cancer analysis, the ORs for high alcohol consumption were greater with 487Glu/Lys genotype compared with Glu/Glu, albeit not.
|
12033531 |
2002 |
|
rs1801516
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the IVS38-8 T/C, 5557 G/A and 5558 A/T polymorphisms and microhaplotypes in the ATM gene with respect to sporadic rectal cancer.
|
12827413 |
2004 |
|
rs1801673
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the IVS38-8 T/C, 5557 G/A and 5558 A/T polymorphisms and microhaplotypes in the ATM gene with respect to sporadic rectal cancer.
|
12827413 |
2004 |
|
rs1048943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The authors evaluated the association of two polymorphisms in the CYP1A1 gene--the noncoding Msp I polymorphism in the 3'-untranslated region and the Ile462Val polymorphism in exon 7--with colon and rectal cancer.
|
15496536 |
2004 |
|
rs2227983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data suggest that the HER-1 R497K and EGFR intron 1 (CA)(n) repeat polymorphisms may be potential indicators of radiosensitivity in patients with rectal cancer treated with chemoradiation.
|
15701846 |
2005 |
|
rs397507444
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This study suggests that MTHFR C677T and A1298C polymorphisms are associated with the reduced risk of colon and rectal cancers, respectively.
|
15829374 |
2005 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This study suggests that MTHFR C677T and A1298C polymorphisms are associated with the reduced risk of colon and rectal cancers, respectively.
|
15829374 |
2005 |
|
rs1801282
|
|
|
0.020 |
GeneticVariation |
BEFREE |
P12A PPARgamma did not significantly interact with BMI, WHR, energy intake, and energy expenditure to alter risk of colon or rectal cancer.
|
15860437 |
2005 |
|
rs1805192
|
|
|
0.020 |
GeneticVariation |
BEFREE |
P12A PPARgamma did not significantly interact with BMI, WHR, energy intake, and energy expenditure to alter risk of colon or rectal cancer.
|
15860437 |
2005 |
|
rs63750114
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified a MLH1 Q701X truncating mutation in the blood lymphocytes of a male who had been diagnosed with rectal cancer at the age of 35.
|
16521201 |
2006 |
|
rs397507444
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We examined independent associations and interactions of folate, B vitamins, methionine, alcohol, and MTHFR polymorphisms (MTHFR C677T and A1298C) with rectal cancer.
|
17245555 |
2007 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We examined independent associations and interactions of folate, B vitamins, methionine, alcohol, and MTHFR polymorphisms (MTHFR C677T and A1298C) with rectal cancer.
|
17245555 |
2007 |
|
rs781230344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cyclin D1 gene G870A polymorphism predicts response to neoadjuvant radiotherapy and prognosis in rectal cancer.
|
17398034 |
2007 |
|
rs35352891
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A 39-year-old male patient with biallelic MYH mutations (p.G272E and p.A359V) received total proctocolectomy for rectal cancer and 36 colorectal polyps.
|
17703316 |
2007 |
|
rs730881833
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A 39-year-old male patient with biallelic MYH mutations (p.G272E and p.A359V) received total proctocolectomy for rectal cancer and 36 colorectal polyps.
|
17703316 |
2007 |
|
rs11568820
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we examine the association of the CDX2 VDR polymorphism (rs11568820) located in the 5'-untranslated region of the gene, and VDR haplotypes, including this polymorphism, with colon and rectal cancer using data from two large case-control studies of colon (N = 1,574 cases and 1,970 controls) and rectal (n = 791 cases and 999 controls) cancer.
|
18086783 |
2007 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GSTP1 Ile105Val polymorphism is a promising marker of potential haematological toxicity in elderly patients with rectal cancer receiving preoperative CRT.
|
18540691 |
2008 |
|
rs397507444
|
|
|
0.060 |
GeneticVariation |
BEFREE |
These results in the present study suggested that polymorphisms of the MTHFR C677T could influence susceptibility to colon or rectal cancer and that there was a coordinated effect between MTHFR A1298C A/A and C677T T/T genotypes among males.
|
18712959 |
2009 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These results in the present study suggested that polymorphisms of the MTHFR C677T could influence susceptibility to colon or rectal cancer and that there was a coordinated effect between MTHFR A1298C A/A and C677T T/T genotypes among males.
|
18712959 |
2009 |
|
rs2066845
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The goal of the current project was to analyze the frequency of selected NOD2 gene variants, including P286S, R702W, G908R, and 1007fs, in the Polish population of patients with rectal cancer.
|
18758419 |
2008 |
|
rs13181
|
|
|
0.030 |
GeneticVariation |
BEFREE |
These interactions were stronger for rectal cancer cases (heterogeneity test P = 0.002 for XPD Asp312Asn and P = 0.03 for XPD Lys751Gln) and remained statistically significant after accounting for multiple testing.
|
19029193 |
2009 |
|
rs1799793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These interactions were stronger for rectal cancer cases (heterogeneity test P = 0.002 for XPD Asp312Asn and P = 0.03 for XPD Lys751Gln) and remained statistically significant after accounting for multiple testing.
|
19029193 |
2009 |
|
rs2227935
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, we detected a significant association of BLM P868L with an increased rectal cancer</span> risk (odds ratio = 1.29, 95% confidence interval 1.02-1.64 and P = 0.04), suggesting a potential cancer-site specificity.
|
19945966 |
2010 |
|
rs3219489
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One SNP, rs3219489:G>C (MUTYH Q324H) seemed to confer an increased risk of rectal cancer in homozygous status (OR=1.52; CI=1.06-2.17).
|
20149637 |
2010 |