Gene: EGFR ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397517094
rs397517094
EGFR
AAA 0.700 GeneticVariation CLINVAR

dbSNP: rs397517098
rs397517098
EGFR
T 0.700 GeneticVariation CLINVAR

dbSNP: rs397517111
rs397517111
EGFR ; EGFR-AS1
CGGGTTG 0.700 CausalMutation CLINVAR

dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR Effects of marine oil-enriched diets on guinea pig megakaryocyte and platelet lipids: effects on thromboxane synthesis and platelet function. 2302402

1990
dbSNP: rs121913444
rs121913444
EGFR
A 0.750 CausalMutation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs28929495
rs28929495
EGFR
C 0.750 GeneticVariation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs121913444
rs121913444
EGFR
A 0.750 CausalMutation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs28929495
rs28929495
EGFR
C 0.750 GeneticVariation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs121913444
rs121913444
EGFR
A 0.750 CausalMutation CLINVAR "EGF receptor gene mutations are common in lung cancers from ""never smokers"" and are associated with sensitivity of tumors to gefitinib and erlotinib." 15329413

2004
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR "EGF receptor gene mutations are common in lung cancers from ""never smokers"" and are associated with sensitivity of tumors to gefitinib and erlotinib." 15329413

2004
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR "EGF receptor gene mutations are common in lung cancers from ""never smokers"" and are associated with sensitivity of tumors to gefitinib and erlotinib." 15329413

2004
dbSNP: rs1057519847
rs1057519847
EGFR
0.800 GeneticVariation BEFREE These findings further characterize a mechanism by which gefitinib treatment of NSCLC harboring EGFR(L858R) leads to a dramatic response to gefitinib. 15492241

2004
dbSNP: rs1057519848
rs1057519848
EGFR
0.800 GeneticVariation BEFREE These findings further characterize a mechanism by which gefitinib treatment of NSCLC harboring EGFR(L858R) leads to a dramatic response to gefitinib. 15492241

2004
dbSNP: rs121434568
rs121434568
EGFR
0.800 GeneticVariation BEFREE These findings further characterize a mechanism by which gefitinib treatment of NSCLC harboring EGFR(L858R) leads to a dramatic response to gefitinib. 15492241

2004
dbSNP: rs121913465
rs121913465
EGFR ; EGFR-AS1
T 0.740 CausalMutation CLINVAR High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan. 15623594

2004
dbSNP: rs397517108
rs397517108
EGFR ; EGFR-AS1
TT 0.740 CausalMutation CLINVAR High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan. 15623594

2004
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib. 15710947

2005
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib. 15710947

2005
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. 15738541

2005
dbSNP: rs28929495
rs28929495
EGFR
C 0.750 GeneticVariation CLINVAR Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer. 15788655

2005
dbSNP: rs121434569
rs121434569
EGFR ; EGFR-AS1
0.100 GeneticVariation BEFREE These inhibitors also show effective inhibition of signaling by T790M-mutant EGFR and killing of NSCLC cells with the T790M mutation. 15897464

2005