Gene: EGFR ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397517094
rs397517094
EGFR
AAA 0.700 GeneticVariation CLINVAR

dbSNP: rs397517098
rs397517098
EGFR
T 0.700 GeneticVariation CLINVAR

dbSNP: rs397517111
rs397517111
EGFR ; EGFR-AS1
CGGGTTG 0.700 CausalMutation CLINVAR

dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR Effects of marine oil-enriched diets on guinea pig megakaryocyte and platelet lipids: effects on thromboxane synthesis and platelet function. 2302402

1990
dbSNP: rs1057519847
rs1057519847
EGFR
0.800 GeneticVariation BEFREE These findings further characterize a mechanism by which gefitinib treatment of NSCLC harboring EGFR(L858R) leads to a dramatic response to gefitinib. 15492241

2004
dbSNP: rs1057519848
rs1057519848
EGFR
0.800 GeneticVariation BEFREE These findings further characterize a mechanism by which gefitinib treatment of NSCLC harboring EGFR(L858R) leads to a dramatic response to gefitinib. 15492241

2004
dbSNP: rs121434568
rs121434568
EGFR
0.800 GeneticVariation BEFREE These findings further characterize a mechanism by which gefitinib treatment of NSCLC harboring EGFR(L858R) leads to a dramatic response to gefitinib. 15492241

2004
dbSNP: rs121913444
rs121913444
EGFR
A 0.750 CausalMutation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs121913444
rs121913444
EGFR
A 0.750 CausalMutation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs121913444
rs121913444
EGFR
A 0.750 CausalMutation CLINVAR "EGF receptor gene mutations are common in lung cancers from ""never smokers"" and are associated with sensitivity of tumors to gefitinib and erlotinib." 15329413

2004
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs28929495
rs28929495
EGFR
C 0.750 GeneticVariation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR "EGF receptor gene mutations are common in lung cancers from ""never smokers"" and are associated with sensitivity of tumors to gefitinib and erlotinib." 15329413

2004
dbSNP: rs28929495
rs28929495
EGFR
C 0.750 GeneticVariation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. 15118125

2004
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. 15118073

2004
dbSNP: rs121913428
rs121913428
EGFR
C 0.740 CausalMutation CLINVAR "EGF receptor gene mutations are common in lung cancers from ""never smokers"" and are associated with sensitivity of tumors to gefitinib and erlotinib." 15329413

2004
dbSNP: rs121913465
rs121913465
EGFR ; EGFR-AS1
T 0.740 CausalMutation CLINVAR High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan. 15623594

2004
dbSNP: rs397517108
rs397517108
EGFR ; EGFR-AS1
TT 0.740 CausalMutation CLINVAR High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan. 15623594

2004
dbSNP: rs1057519847
rs1057519847
EGFR
0.800 GeneticVariation BEFREE Here, we show that L858R and deletion mutant EGFR proteins found in NSCLC interact with the chaperone and are sensitive to degradation following Hsp90 inhibition. 16024644

2005
dbSNP: rs1057519848
rs1057519848
EGFR
0.800 GeneticVariation BEFREE Here, we show that L858R and deletion mutant EGFR proteins found in NSCLC interact with the chaperone and are sensitive to degradation following Hsp90 inhibition. 16024644

2005
dbSNP: rs121434568
rs121434568
EGFR
0.800 GeneticVariation BEFREE Here, we show that L858R and deletion mutant EGFR proteins found in NSCLC interact with the chaperone and are sensitive to degradation following Hsp90 inhibition. 16024644

2005
dbSNP: rs28929495
rs28929495
EGFR
T 0.750 CausalMutation CLINVAR Mutations in the tyrosine kinase domain of the EGFR gene associated with gefitinib response in non-small-cell lung cancer. 16011858

2005
dbSNP: rs28929495
rs28929495
EGFR
C 0.750 GeneticVariation CLINVAR Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer. 15788655

2005