Gene: PIK3CA ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589

2012
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. 21430269

2011
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR PIK3CA mutation status in Japanese lung cancer patients. 16930767

2006
dbSNP: rs121913281
rs121913281
PIK3CA
T 0.700 CausalMutation CLINVAR

dbSNP: rs397517202
rs397517202
PIK3CA
G 0.700 CausalMutation CLINVAR

dbSNP: rs121913273
rs121913273
PIK3CA
C 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913283
rs121913283
PIK3CA
A 0.700 GeneticVariation CLINVAR

dbSNP: rs397517200
rs397517200
PIK3CA
A 0.700 GeneticVariation CLINVAR