Gene: TERT ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13167280
rs13167280
TERT
A 0.700 GeneticVariation GWASCAT Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. 31326317

2019
dbSNP: rs7705526
rs7705526
TERT
A 0.700 GeneticVariation GWASCAT Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. 31326317

2019
dbSNP: rs2736100
rs2736100
TERT
0.060 GeneticVariation BEFREE Minor allele of rs2736098 and rs2736100 in TERT gene and interaction between the two SNP were associated with increased risk of NSCLC risk. 27154632

2016
dbSNP: rs2736100
rs2736100
TERT
0.060 GeneticVariation BEFREE Of these regions, single-nucleotide polymorphisms (SNPs), especially rs2736100 located in the telomerase reverse transcriptase (TERT) gene show unique and significant association with non-small cell lung cancer (NSCLC) in a few subpopulations including women, nonsmokers, East Asians and those with adenocarcinoma. 26554909

2015
dbSNP: rs2736100
rs2736100
TERT
0.060 GeneticVariation BEFREE The rs2736100-C allele was significantly associated with EGFRmut(+) NSCLC [OR, 1.52; 95% confidence interval (CI), 1.28-1.80; P = 1.6 × 10(-6)] but not EGFRmut(-) NSCLC (OR = 1.07, 95% CI, 0.92-1.24, P = 0.4). 26149460

2015
dbSNP: rs2736100
rs2736100
TERT
0.060 GeneticVariation BEFREE We additionally found an increased risk of non-small cell lung cancer and lung adenocarcinoma strongly associated with rs2736100. 24590268

2014
dbSNP: rs2736100
rs2736100
TERT
0.060 GeneticVariation BEFREE In the current study, we investigated the association between rs2736100T/G and NSCLC in 1,552 NSCLC and 1,602 healthy controls. 24420154

2014
dbSNP: rs2736100
rs2736100
TERT
0.060 GeneticVariation BEFREE To test this hypothesis, we genotyped two most significant SNPs reported in Caucasians, rs2736100A/C and rs402710C/T at 5p15.33, in a case-control study with 1221 non-small cell lung cancer (NSCLC) cases and 1344 cancer-free controls in a Chinese population. 19369581

2009
dbSNP: rs2853677
rs2853677
TERT
0.020 GeneticVariation BEFREE The results of this study suggested that rs2853677 of TERT signifies association in multiple cancers and suggests that it can become potential marker for diagnosis of non-small cell lung cancer and leukemia. 31126249

2019
dbSNP: rs2853677
rs2853677
TERT
0.020 GeneticVariation BEFREE Our results indicated that rs2853677 and rs2853691 in the <i>TERT</i> gene might be associated with NSCLC in this Chinese Han population. 29928145

2018
dbSNP: rs2736098
rs2736098
TERT
0.020 GeneticVariation BEFREE Minor allele of rs2736098 and rs2736100 in TERT gene and interaction between the two SNP were associated with increased risk of NSCLC risk. 27154632

2016
dbSNP: rs2736098
rs2736098
TERT
0.020 GeneticVariation BEFREE Association between the telomerase reverse transcriptase (TERT) rs2736098 polymorphism and cancer risk: evidence from a case-control study of non-small-cell lung cancer and a meta-analysis. 24260099

2013
dbSNP: rs2853669
rs2853669
TERT
0.010 GeneticVariation BEFREE The association of rs2853669 with telomerase reverse transcriptase (TERT) mRNA level and relative telomere length (RTL) was analysed using resected tumour samples from 250 NSCLC patients. 31446212

2019
dbSNP: rs2853691
rs2853691
TERT
0.010 GeneticVariation BEFREE Our results indicated that rs2853677 and rs2853691 in the <i>TERT</i> gene might be associated with NSCLC in this Chinese Han population. 29928145

2018