Gene: CD274 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4143815
rs4143815
CD274
0.020 GeneticVariation BEFREE Among the three SNPs, the rs4143815 genotype CC was statistically associated with positive 22C3 PD-L1 labeling in NSCLCs. 28851662

2017
dbSNP: rs4143815
rs4143815
CD274
0.020 GeneticVariation BEFREE Moreover, the C/C and C/G genotypes of PD-L1 rs4143815 were significantly associated with better ORR and PFS in NSCLC patients treated with nivolumab. 28332580

2017
dbSNP: rs2297136
rs2297136
CD274
0.010 GeneticVariation BEFREE Dual‑luciferase reporter assays showed that rs2297136 and rs4742098 in the B7‑H1 3'‑UTR contributed to the occurrence of NSCLC through disrupting the interaction between miR‑296‑5p, miR‑138 and B7‑H1 mRNA. 28677815

2017
dbSNP: rs4742098
rs4742098
CD274
0.010 GeneticVariation BEFREE Dual‑luciferase reporter assays showed that rs2297136 and rs4742098 in the B7‑H1 3'‑UTR contributed to the occurrence of NSCLC through disrupting the interaction between miR‑296‑5p, miR‑138 and B7‑H1 mRNA. 28677815

2017