|
rs2043211
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined <i>PTPN22</i> rs2476601 (p.Arg620Trp), <i>NLRP3</i> rs35829419 (p.Gln705Lys), and <i>CARD8</i> rs2043211 (p.Cys10Ter) in 66 subjects with coexisting T1D and CD, 65 subjects with T1D who did not develop CD, 67 subjects diagnosed only with CD and 127 healthy unrelated Slovenian individuals.
|
30915320 |
2019 |
|
rs1161457931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C282Y allele frequency was significantly increased in CD compared with controls (1.1% vs 0.2%, P = .001), whereas H63D and A736V allele frequencies were similar among patients and controls (P = .92 and .84, respectively).
|
29194702 |
2018 |
|
rs1208663703
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C282Y allele frequency was significantly increased in CD compared with controls (1.1% vs 0.2%, P = .001), whereas H63D and A736V allele frequencies were similar among patients and controls (P = .92 and .84, respectively).
|
29194702 |
2018 |
|
rs738409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PNPLA3 rs738409 Polymorphism Predicts Development and Severity of Hepatic Steatosis but Not Metabolic Syndrome in Celiac Disease.
|
30189691 |
2018 |
|
rs855791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C282Y allele frequency was significantly increased in CD compared with controls (1.1% vs 0.2%, P = .001), whereas H63D and A736V allele frequencies were similar among patients and controls (P = .92 and .84, respectively).
|
29194702 |
2018 |
|
rs11100722
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we analyze IL-15 and IL-15Rα genes in samples from the Spanish Consortium for Genetics of Celiac Disease (CEGEC) collection, identifying two regulatory single-nucleotide polymorphisms (SNP) that might be associated with celiac disease: rs4956400 (p-value 0.0112, OR 1.21, 95% CI 1.04-1.40) and rs11100722 (p-value 0.0087, OR 1.24, 95% CI 1.06-1.45), both located upstream the IL15 gene.
|
28738233 |
2017 |
|
rs1800796
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to investigate polymorphisms in the genes responsible for encoding cytokines interleukin-6 (IL-6) (-572G/C) (rs1800796) and IL-17 (-197A/G) (rs2275913) in patients with celiac disease (CD).
|
28928101 |
2017 |
|
rs2275913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to investigate polymorphisms in the genes responsible for encoding cytokines interleukin-6 (IL-6) (-572G/C) (rs1800796) and IL-17 (-197A/G) (rs2275913) in patients with celiac disease (CD).
|
28928101 |
2017 |
|
rs4956400
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we analyze IL-15 and IL-15Rα genes in samples from the Spanish Consortium for Genetics of Celiac Disease (CEGEC) collection, identifying two regulatory single-nucleotide polymorphisms (SNP) that might be associated with celiac disease: rs4956400 (p-value 0.0112, OR 1.21, 95% CI 1.04-1.40) and rs11100722 (p-value 0.0087, OR 1.24, 95% CI 1.06-1.45), both located upstream the IL15 gene.
|
28738233 |
2017 |
|
rs10754558
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, stratification by disease type showed a significant association of the NLRP3 rs10754558 C allele with SLE (OR = 1.465 95% CI = 1.144-1.875, p = 0.002) but not with gout and celiac disease.
|
27060062 |
2016 |
|
rs1800693
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One TNFRSF1A variant was identified (c.625+10A>G, rs1800693), but not associated with CD.
|
25915602 |
2015 |
|
rs187238
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Given the IL-18 biological role, and since a few studies have previously suggested its involvement in CD, in order to investigate the role of IL18 gene in the susceptibility to CD we have performed a case-control study, analyzing two IL18 gene promoter polymorphisms, previously reported to impair the transcriptional activity of the gene, (-137G > C and -607C > A, rs187238 and rs1946518 respectively).
|
25374428 |
2015 |
|
rs1946518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Given the IL-18 biological role, and since a few studies have previously suggested its involvement in CD, in order to investigate the role of IL18 gene in the susceptibility to CD we have performed a case-control study, analyzing two IL18 gene promoter polymorphisms, previously reported to impair the transcriptional activity of the gene, (-137G > C and -607C > A, rs187238 and rs1946518 respectively).
|
25374428 |
2015 |
|
rs9939609
|
|
|
0.010 |
GeneticVariation |
BEFREE |
FTO Polymorphism rs9939609 Contributes to Weight Changes in Children With Celiac Disease on Gluten-Free Diet.
|
26222659 |
2015 |
|
rs10484718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this work was to evaluate the expression levels of these two genes in duodenal mucosa of active and treated CD patients and in controls, and to determine whether SNPs (rs802734, rs55743914, rs72975916, rs10484718 and rs9491896) associated with CD have any influence on gene expression.
|
23820479 |
2014 |
|
rs10491434
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These four variants are implicated in complex phenotypes such as ulcerative colitis and AIDS progression disease (rs10491434), Celiac disease (rs2762051), Crohn's disease, IgA nephropathy and early-onset inflammatory bowel disease (rs713875) and height (rs6569648).
|
24911414 |
2014 |
|
rs4686484
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We later found significantly low levels of LPP mRNA in CeD biopsies compared with controls, thus our results suggest that rs4686484 is the functional variant in this locus, while LPP expression is decreased in CeD.
|
24334606 |
2014 |
|
rs72975916
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this work was to evaluate the expression levels of these two genes in duodenal mucosa of active and treated CD patients and in controls, and to determine whether SNPs (rs802734, rs55743914, rs72975916, rs10484718 and rs9491896) associated with CD have any influence on gene expression.
|
23820479 |
2014 |
|
rs9491896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this work was to evaluate the expression levels of these two genes in duodenal mucosa of active and treated CD patients and in controls, and to determine whether SNPs (rs802734, rs55743914, rs72975916, rs10484718 and rs9491896) associated with CD have any influence on gene expression.
|
23820479 |
2014 |
|
rs10930046
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our study we analyzed IFIH1 rs6432714 and rs10930046 SNPs in T1D patients stratified for the presence of celiac disease and autoimmune thyroid disease.
|
23246693 |
2013 |
|
rs6432714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our study we analyzed IFIH1 rs6432714 and rs10930046 SNPs in T1D patients stratified for the presence of celiac disease and autoimmune thyroid disease.
|
23246693 |
2013 |
|
rs11552708
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A regulatory SNP in TNFSF13 (rs11552708) is associated with CD (p = 0.01, OR = 0.7).
|
22136669 |
2012 |
|
rs1801198
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A set of 10 gene polymorphisms (MTHFR rs1801133, MTR rs1805087, MTHFD1 rs2236225, MTRR rs1801394, CBS 844ins68, BHMT1 rs7356530 and rs3733890, BHMT2 rs526264 and rs625879, and TCN2 rs1801198) was tested in 134 patients with CD and 160 matched healthy controls.
|
21688148 |
2012 |
|
rs601338
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association study of FUT2 (rs601338) with celiac disease and inflammatory bowel disease in the Finnish population.
|
23075394 |
2012 |
|
rs1248696
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study does not support the effect of the R30Q DLG5 variant in CeD or IBD predisposition in the Spanish population.
|
20796250 |
2011 |