|
rs774229224
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The role of factor XIII Val 34 Leu in the pathogenesis of cerebral infarction and primary intracerebral hemorrhage is unknown.
|
9550516 |
1998 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The mutant MTHFR heterozygous 677C/T</span> carriers were increased in patients with cerebral infarction compared with controls (53.9% vs. 36.9%, 0.01 < P < 0.025).
|
10929044 |
2000 |
|
rs1188383936
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The mutant MTHFR heterozygous 677C/T</span> carriers were increased in patients with cerebral infarction compared with controls (53.9% vs. 36.9%, 0.01 < P < 0.025).
|
10929044 |
2000 |
|
rs899127658
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In young adults, the PT(G20210A) variant and, to a lesser extent, the FV(G1691A) mutation may represent risk factors for PFO-related cerebral infarcts.
|
12511746 |
2003 |
|
rs4986790
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We studied the prevalence of two common polymorphisms of the TLR4 gene (Asp299Gly and Thr399Ile) in 3 independent study populations: (1.) in a cross-sectional study including 769 patients either with type 1 or type 2 diabetes mellitus, of whom 56 (7.2%) had a history of cerebral ischemia (study 1), (2.) a case-control study (study 2) including 128 consecutive patients with cerebral ischemia, mean age 60 +/- 10.9 years and 139 control subjects, and (3.) a case-control study (study 3) including 171 young adults aged < 50 years with cerebral ischemia and 204 control individuals.
|
15258789 |
2004 |
|
rs4986791
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We studied the prevalence of two common polymorphisms of the TLR4 gene (Asp299Gly and Thr399Ile) in 3 independent study populations: (1.) in a cross-sectional study including 769 patients either with type 1 or type 2 diabetes mellitus, of whom 56 (7.2%) had a history of cerebral ischemia (study 1), (2.) a case-control study (study 2) including 128 consecutive patients with cerebral ischemia, mean age 60 +/- 10.9 years and 139 control subjects, and (3.) a case-control study (study 3) including 171 young adults aged < 50 years with cerebral ischemia and 204 control individuals.
|
15258789 |
2004 |
|
rs1042579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thrombomodulin Ala455Val Polymorphism and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.
|
15574195 |
2004 |
|
rs147377392
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thrombomodulin Ala455Val Polymorphism and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.
|
15574195 |
2004 |
|
rs1799945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hemochromatosis-causing mutations C282Y and H63D are not risk factors for atherothrombotic cerebral infarction.
|
15990686 |
2005 |
|
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hemochromatosis-causing mutations C282Y and H63D are not risk factors for atherothrombotic cerebral infarction.
|
15990686 |
2005 |
|
rs768963
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Analysis demonstrated that there were significant differences in the overall distribution of genotypes and dominant or recessive models of rs2271875 and rs768963 between the CI and the non-CI groups.
|
17249521 |
2006 |
|
rs2238634
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, the C-T-C haplotype of rs768963-rs2238634-rs4806942 was significantly more frequent in the CI group (23.0%) than in the non-CI group (17.7%).
|
17249521 |
2006 |
|
rs2271875
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis demonstrated that there were significant differences in the overall distribution of genotypes and dominant or recessive models of rs2271875 and rs768963 between the CI and the non-CI groups.
|
17249521 |
2006 |
|
rs4806942
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, the C-T-C haplotype of rs768963-rs2238634-rs4806942 was significantly more frequent in the CI group (23.0%) than in the non-CI group (17.7%).
|
17249521 |
2006 |
|
rs662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the human serum paraoxonase polymorphisms, Q192R and L55M, are not associated with the risk of cerebral infarction in Chinese Han population.
|
16808888 |
2006 |
|
rs854560
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the human serum paraoxonase polymorphisms, Q192R and L55M, are not associated with the risk of cerebral infarction in Chinese Han population.
|
16808888 |
2006 |
|
rs1799883
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genotypes for these polymorphisms, especially for the 2445G-->A (Ala54Thr) polymorphism of FABP2, may prove informative for the prediction of genetic risk for atherothrombotic cerebral infarction among such individuals.
|
18506375 |
2008 |
|
rs2070744
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The Chi-square test, multivariable logistic regression analysis with adjustment for age, sex, body mass index, and the prevalence of hypertension, hypercholesterolemia, and diabetes mellitus, as well as a stepwise forward selection procedure revealed that the 2445G-->A (Ala54Thr) polymorphism (rs1799883) of FABP2, the -108/3G-->4G polymorphism of IPF1 (S82168), the A-->G (Thr94Ala) polymorphism (rs2241883) of FABP1, the G-->A (Asp2213Asn) polymorphism (rs529038) of ROS1, the -11377C-->G polymorphism (rs266729) of ADIPOQ, the 162A-->C polymorphism (rs4769055) of ALOX5AP, the -786T-->C polymorphism (rs2070744) of NOS3, and the 3279C-->T polymorphism (rs7291467) of LGALS2 were associated (P<0.05) with the prevalence of atherothrombotic cerebral infarction.
|
18506375 |
2008 |
|
rs2241883
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The Chi-square test, multivariable logistic regression analysis with adjustment for age, sex, body mass index, and the prevalence of hypertension, hypercholesterolemia, and diabetes mellitus, as well as a stepwise forward selection procedure revealed that the 2445G-->A (Ala54Thr) polymorphism (rs1799883) of FABP2, the -108/3G-->4G polymorphism of IPF1 (S82168), the A-->G (Thr94Ala) polymorphism (rs2241883) of FABP1, the G-->A (Asp2213Asn) polymorphism (rs529038) of ROS1, the -11377C-->G polymorphism (rs266729) of ADIPOQ, the 162A-->C polymorphism (rs4769055) of ALOX5AP, the -786T-->C polymorphism (rs2070744) of NOS3, and the 3279C-->T polymorphism (rs7291467) of LGALS2 were associated (P<0.05) with the prevalence of atherothrombotic cerebral infarction.
|
18506375 |
2008 |
|
rs1059703
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An initial chi(2) test (false discovery rate <0.05) and subsequent multivariable logistic-regression analysis with adjustment for conventional risk factors (P<0.05) revealed that the -14C-->T polymorphism (rs1800977) of ABCA1, the A-->C (rs3027898) and C-->T (Ser532Leu, rs1059703) polymorphisms of IRAK1, and the G-->C (Cys2229Ser) polymorphism (rs619203) of ROS1 were significantly associated with atherothrombotic cerebral infarction; that the -428G-->A polymorphism (rs710968) of LIMK1 was significantly associated with intracerebral hemorrhage; and that the 13989A-->G (Ile118Val) polymorphism (NC_000007.12) of CYP3A4 was significantly associated with subarachnoid hemorrhage.
|
18566305 |
2008 |
|
rs1799895
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a haplotype-based case control on rs13306703, rs699473 and rs1799895 in women, the frequency of the C-C-C haplotype was significantly higher in the CI group than in the control group (men; 51.5% vs 51.4% p=0.9865, women; 62.5% vs 49.7% p=0.0108).
|
19200140 |
2008 |
|
rs1801273
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes for these polymorphisms, especially for the 2445G-->A (Ala54Thr) polymorphism of FABP2, may prove informative for the prediction of genetic risk for atherothrombotic cerebral infarction among such individuals.
|
18506375 |
2008 |
|
rs2108622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results of this study indicate that, in Japanese men, CI is associated with the G allele of rs2108622 and, in addition, that the T-C-G haplotype appears to be a useful genetic marker for CI.
|
18787519 |
2008 |
|
rs2536512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among women, there were significant differences between the CI and control group in overall distribution of alleles for rs699473 (men: OR=1.031, 95% CI: 0.705-1.506, women: OR=1.916, 95% CI: 1.196-3.071) and rs2536512 (men: OR=0.774, 95% CI: 0.523-1.146, women: OR=2.107, 95% CI: 1.227-3.462).
|
19200140 |
2008 |
|
rs266729
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Chi-square test, multivariable logistic regression analysis with adjustment for age, sex, body mass index, and the prevalence of hypertension, hypercholesterolemia, and diabetes mellitus, as well as a stepwise forward selection procedure revealed that the 2445G-->A (Ala54Thr) polymorphism (rs1799883) of FABP2, the -108/3G-->4G polymorphism of IPF1 (S82168), the A-->G (Thr94Ala) polymorphism (rs2241883) of FABP1, the G-->A (Asp2213Asn) polymorphism (rs529038) of ROS1, the -11377C-->G polymorphism (rs266729) of ADIPOQ, the 162A-->C polymorphism (rs4769055) of ALOX5AP, the -786T-->C polymorphism (rs2070744) of NOS3, and the 3279C-->T polymorphism (rs7291467) of LGALS2 were associated (P<0.05) with the prevalence of atherothrombotic cerebral infarction.
|
18506375 |
2008 |