Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1024611
rs1024611
0.010 GeneticVariation BEFREE This meta-analysis was performed to evaluate the relationships between the monocyte chemoattractant protein-1 (MCP-1) -2518A>G (rs1024611 A>G) polymorphism and its serum levels, and the risk of cerebral infarction. 24720638

2014

dbSNP: rs10304
rs10304
0.010 GeneticVariation BEFREE The genotypic distribution of rs10304 for men showed a significant difference between the control and CI groups. 23033319

2012

dbSNP: rs1042579
rs1042579
0.010 GeneticVariation BEFREE Thrombomodulin Ala455Val Polymorphism and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study. 15574195

2004

dbSNP: rs1044006
rs1044006
0.010 GeneticVariation BEFREE Statistical analyses showed that rs1044009 and rs1044006 were associated with the risk of cerebral infarction disease in the Chinese Han agedness population. 27370894

2016

dbSNP: rs1044009
rs1044009
0.010 GeneticVariation BEFREE Statistical analyses showed that rs1044009 and rs1044006 were associated with the risk of cerebral infarction disease in the Chinese Han agedness population. 27370894

2016

dbSNP: rs1050283
rs1050283
0.010 GeneticVariation BEFREE Association of the LOX-1 rs1050283 Polymorphism with Risk for Atherosclerotic Cerebral Infarction and its Effect on sLOX-1 and LOX-1 Expression in a Chinese Population. 27840386

2017

dbSNP: rs10507391
rs10507391
0.010 GeneticVariation BEFREE The results of the meta-analysis indicate that ALOX5AP rs10507391/SG13S114 A>T polymorphism is not associated with the risk of cerebral infarction in the Chinese population. 25242267

2015

dbSNP: rs1051266
rs1051266
0.010 GeneticVariation BEFREE We selected three known RFC-1 polymorphisms (-43C>T, 80A>G, 696T>C) and investigated their relationship to cerebral infarction in the Korean population. 25659099

2015

dbSNP: rs1057335
rs1057335
0.010 GeneticVariation BEFREE Our findings suggest that the α2AP Arg407Lys polymorphism could be involved in the pathogenesis of cerebral ischemia and its outcomes. 29306602

2019

dbSNP: rs1059703
rs1059703
0.010 GeneticVariation BEFREE An initial chi(2) test (false discovery rate <0.05) and subsequent multivariable logistic-regression analysis with adjustment for conventional risk factors (P<0.05) revealed that the -14C-->T polymorphism (rs1800977) of ABCA1, the A-->C (rs3027898) and C-->T (Ser532Leu, rs1059703) polymorphisms of IRAK1, and the G-->C (Cys2229Ser) polymorphism (rs619203) of ROS1 were significantly associated with atherothrombotic cerebral infarction; that the -428G-->A polymorphism (rs710968) of LIMK1 was significantly associated with intracerebral hemorrhage; and that the 13989A-->G (Ile118Val) polymorphism (NC_000007.12) of CYP3A4 was significantly associated with subarachnoid hemorrhage. 18566305

2008

dbSNP: rs10780199
rs10780199
0.010 GeneticVariation BEFREE Furthermore, the C-C-G and G-G-G haplotypes of rs7042521-rs11137351-rs10780199 were significantly more frequent in the CI group than in the control group (p = 0.024 and p < 0.000). 21166801

2010

dbSNP: rs10846744
rs10846744
0.010 GeneticVariation BEFREE The frequency of the C allele for rs10846744 and that of the T allele for rs2278986 appeared to be significantly increased in the CHD group (OR: 1.416, 95%CI: 1.128-1.778, P=0.0058 and OR: 1.681, 95%CI: 1.327-2.130, P<0.0001, respectively). 28552715

2017

dbSNP: rs10898909
rs10898909
0.010 GeneticVariation BEFREE For all subjects, the frequency of the T-A-G haplotype (rs1783596-rs4382936-rs10898909) was also significantly higher (P=0.031), whereas the frequency of the T-C-G haplotype (rs1783596-rs4382936-rs10898909) was significantly lower (P=0.029) in the CI patients than in the control 1 group. 19763137

2009

dbSNP: rs11053646
rs11053646
0.010 GeneticVariation BEFREE The study indicated that the G501C variant in LOX-1 gene may be associated with susceptibility to cerebral infarction, independent of other common risk factors, in northern Chinese Han population. 24661313

2014

dbSNP: rs11137351
rs11137351
0.010 GeneticVariation BEFREE Furthermore, the C-C-G and G-G-G haplotypes of rs7042521-rs11137351-rs10780199 were significantly more frequent in the CI group than in the control group (p = 0.024 and p < 0.000). 21166801

2010

dbSNP: rs112735431
rs112735431
0.010 GeneticVariation BEFREE Diseases associated with the RNF213 gene include moyamoya disease, with the p.R4810K (c.14429G>A, rs112735431) homozygous variant thought to be the most pathogenic and significantly associated with severe manifestation such as early onset or cerebral infarction at onset. 31806452

2020

dbSNP: rs1131882
rs1131882
0.010 GeneticVariation BEFREE We found that rs768963 polymorphism was significantly more frequent in the CI group than in the non-CI group and the T-T-G-T haplotype of C795T-T924C-G1686A-rs768963 was significantly less frequent in the CI subjects (0.238 versus 0.339; OR 0.617 [95%CI 0.444-0.856]). 25557379

2015

dbSNP: rs11614913
rs11614913
0.010 GeneticVariation BEFREE Thus, the SNP rs11614913 is significantly associated with moyamoya disease, as well as cerebral infarction and adult age in patients with moyamoya disease. 22659075

2012

dbSNP: rs11833579
rs11833579
0.010 GeneticVariation BEFREE This is the first study to show an association of rs11833579 with multiple episodes of cerebral ischemia of atherothrombotic origin, and of rs11833579 and rs12425791 with short duration of ischemia. 22011019

2012

dbSNP: rs1188383936
rs1188383936
F2
0.020 GeneticVariation BEFREE The aim of this study is to determine the role of hereditary thrombophilic factors including factor V Leiden A1691G (FVL), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T gene mutations in patients with stroke because of cerebral infarct. 19263510

2009

dbSNP: rs1188383936
rs1188383936
F2
0.020 GeneticVariation BEFREE The mutant MTHFR heterozygous 677C/T</span> carriers were increased in patients with cerebral infarction compared with controls (53.9% vs. 36.9%, 0.01 < P < 0.025). 10929044

2000

dbSNP: rs1207570776
rs1207570776
0.010 GeneticVariation BEFREE The aim of this study is to determine the role of hereditary thrombophilic factors including factor V Leiden A1691G (FVL), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T gene mutations in patients with stroke because of cerebral infarct. 19263510

2009

dbSNP: rs1217691063
rs1217691063
0.040 GeneticVariation BEFREE The methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms, which are associated with hyperhomocysteinemia and nitric oxide (NO) deficiency (which is related to atherothrombosis and cerebral ischemia), have not been studied in moyamoya disease. 25098357

2014

dbSNP: rs1217691063
rs1217691063
0.040 GeneticVariation BEFREE The mutant MTHFR heterozygous 677C/T</span> carriers were increased in patients with cerebral infarction compared with controls (53.9% vs. 36.9%, 0.01 < P < 0.025). 10929044

2000

dbSNP: rs1217691063
rs1217691063
0.040 GeneticVariation BEFREE The aim of this study is to determine the role of hereditary thrombophilic factors including factor V Leiden A1691G (FVL), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T gene mutations in patients with stroke because of cerebral infarct. 19263510

2009