Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.020 | GeneticVariation | BEFREE | Frequency of I655V SNP of HER-2/<i>neu</i> in colorectal cancer: a study from India. | 30622849 | 2019 |
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0.020 | GeneticVariation | BEFREE | PCR--RFLP analysis of the Val(655)Ile single nucleotide polymorphism demonstrated that allele frequencies were identical between colorectal cancer patients and a control group of Caucasian subjects (Ile=0.80 and Val=0.20 in each case), indicating that it is not related to the risk of developing colorectal cancer in this population. | 11870539 | 2002 |
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0.010 | GeneticVariation | BEFREE | Among the 6 HER2-positive CRCs, <i>KRAS</i> and <i>PIK3CA</i> mutations were detected in 1 (17%; G13D) and 2 (33.3%; 1 Q546R and 1 H1047R) patients, respectively. | 31692488 | 2019 |
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0.010 | GeneticVariation | BEFREE | Among the 6 HER2-positive CRCs, <i>KRAS</i> and <i>PIK3CA</i> mutations were detected in 1 (17%; G13D) and 2 (33.3%; 1 Q546R and 1 H1047R) patients, respectively. | 31692488 | 2019 |
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0.010 | GeneticVariation | BEFREE | Among the 6 HER2-positive CRCs, <i>KRAS</i> and <i>PIK3CA</i> mutations were detected in 1 (17%; G13D) and 2 (33.3%; 1 Q546R and 1 H1047R) patients, respectively. | 31692488 | 2019 |
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0.010 | GeneticVariation | BEFREE | We tested 85 Formalin Fixed and Paraffin Embbeded (FFPE) samples and we detected three HER2-V842I mutations in colorectal carcinoma (CRC), ovarian carcinoma, and pancreatic carcinoma patients, respectively, and a HER2-L755M mutation in a CRC specimen. | 26287187 | 2015 |
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0.010 | GeneticVariation | BEFREE | We tested 85 Formalin Fixed and Paraffin Embbeded (FFPE) samples and we detected three HER2-V842I mutations in colorectal carcinoma (CRC), ovarian carcinoma, and pancreatic carcinoma patients, respectively, and a HER2-L755M mutation in a CRC specimen. | 26287187 | 2015 |