rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
The major aim of this study was to evaluate the performance of anti-BRAF V600E (VE1) antibody in colorectal tumors with and without KRAS mutation.
|
29127628 |
2019 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
BRAF V600E mutation testing of colorectal tumors demonstrating aberrant MLH1 protein expression by IHC was the most common secondary tumor test, with 53% of laboratories performing the test; 15% of laboratories also applied the BRAF V600E test to endometrial tumors with aberrant MLH1 expression despite no evidence for its utility.
|
30294856 |
2018 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Our results support the use of VE1 IHC for identification of colorectal neoplasms harboring the BRAF V600E mutation.
|
25517872 |
2015 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
To verify the technical characteristics of the microarray system for the correct identification of the KRAS mutational status at the two hotspot codons 12 and 13 and of the BRAF(V600E) mutation in colorectal tumor, we selected 75 samples previously characterized by conventional and CO-amplification at Lower Denaturation temperature-PCR (COLD-PCR) followed by High Resolution Melting analysis and direct sequencing.
|
23536897 |
2013 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Evaluation of high-resolution melting analysis as a diagnostic tool to detect the BRAF V600E mutation in colorectal tumors.
|
19213871 |
2009 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Secondly, considering the alternative possibility, we identified genes whose DNA hypermethylation was closely linked to BRAF(V600E) and CIMP in 235 primary colorectal tumors.
|
20027224 |
2009 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Rac1b overexpression and B-Raf(V600E) are significantly associated in primary colorectal tumors (P = .008) and colorectal cell lines.
|
18602919 |
2008 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
In addition, a significant association between mismatch-repair (MMR) deficiency and the V599E mutation in colorectal tumors has been found.
|
14654916 |
2004 |
rs113488022
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Recently, a V599E hotspot mutation within the BRAF gene was reported in a high percentage of colorectal tumors and significantly associated to defective mismatch repair (MMR).
|
14668801 |
2003 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The major aim of this study was to evaluate the performance of anti-BRAF V600E (VE1) antibody in colorectal tumors with and without KRAS mutation.
|
29127628 |
2019 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
BRAF V600E mutation testing of colorectal tumors demonstrating aberrant MLH1 protein expression by IHC was the most common secondary tumor test, with 53% of laboratories performing the test; 15% of laboratories also applied the BRAF V600E test to endometrial tumors with aberrant MLH1 expression despite no evidence for its utility.
|
30294856 |
2018 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Our results support the use of VE1 IHC for identification of colorectal neoplasms harboring the BRAF V600E mutation.
|
25517872 |
2015 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
To verify the technical characteristics of the microarray system for the correct identification of the KRAS mutational status at the two hotspot codons 12 and 13 and of the BRAF(V600E) mutation in colorectal tumor, we selected 75 samples previously characterized by conventional and CO-amplification at Lower Denaturation temperature-PCR (COLD-PCR) followed by High Resolution Melting analysis and direct sequencing.
|
23536897 |
2013 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Evaluation of high-resolution melting analysis as a diagnostic tool to detect the BRAF V600E mutation in colorectal tumors.
|
19213871 |
2009 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Secondly, considering the alternative possibility, we identified genes whose DNA hypermethylation was closely linked to BRAF(V600E) and CIMP in 235 primary colorectal tumors.
|
20027224 |
2009 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Rac1b overexpression and B-Raf(V600E) are significantly associated in primary colorectal tumors (P = .008) and colorectal cell lines.
|
18602919 |
2008 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In addition, a significant association between mismatch-repair (MMR) deficiency and the V599E mutation in colorectal tumors has been found.
|
14654916 |
2004 |
rs121913377
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Recently, a V599E hotspot mutation within the BRAF gene was reported in a high percentage of colorectal tumors and significantly associated to defective mismatch repair (MMR).
|
14668801 |
2003 |