Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease. 14989558

2003

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE An endothelial nitric oxide synthase gene (NOS3) polymorphism in exon 7 (G894T), resulting in Glu298Asp substitution at protein level, has been associated with myocardial infarction, hypertension and coronary atherosclerosis in some populations. 12113283

2002

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Glu298-->Asp polymorphism of the eNOS gene appears to be associated with the presence, extent, and severity of angiographically assessed coronary artery disease. 12010932

2002

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is associated with coronary heart disease in younger individuals with high atherosclerotic risk profile. 11755935

2002

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Lack of association between the Glu298Asp variant of the endothelial nitric oxide synthase gene and the risk of coronary artery disease among Taiwanese. 11802531

2001

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Relationship of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and early-onset coronary artery disease. 11579346

2001

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE We recently identified two endothelial nitric oxide synthase (eNOS) gene polymorphisms, Glu298Asp and T-786-->C, which are independently associated with coronary spasm. eNOS gene intron 4b/a polymorphism is also reported to be involved in smoking-dependent coronary artery disease. 10979242

2000

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE A common variant of the endothelial nitric oxide synthase (Glu298-->Asp) is a major risk factor for coronary artery disease in the UK. 10510054

1999

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE The Glu-298-->Asp (894G-->T) mutation at exon 7 of the endothelial nitric oxide synthase gene and coronary artery disease. 10475066

1999

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coronary artery disease--case reports. 10451235

1999

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Recently, a common polymorphism in exon 7 of the eNOS gene (894G-->T) has been reported to be a strong risk factor for coronary artery disease. 9731617

1998