|
rs7902091
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Significant interaction with maternal CMV infection was found for rs7902091 (P(SNP × CMV)=7.3 × 10(-7)) in CTNNA3, a gene not previously implicated in schizophrenia, stressing the importance of including environmental factors in genetic studies.
|
23358160 |
2014 |
|
rs7902091
|
|
A |
0.710 |
GeneticVariation |
GWASCAT |
Significant interaction with maternal CMV infection was found for rs7902091 (P(SNP × CMV)=7.3 × 10(-7)) in CTNNA3, a gene not previously implicated in schizophrenia, stressing the importance of including environmental factors in genetic studies.
|
23358160 |
2014 |
|
rs5743708
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The TLR2-Arg753Gln SNP was genotyped in 181 patients after bone marrow transplantation: 83 and 98 patients with and without CMV infection, respectively.
|
31656159 |
2019 |
|
rs5743708
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Among various TLR2, TLR4 and TLR9 polymorphisms, TLR2 2258 G>A SNP seems to be an important factor associated with increased risk of congenital HCMV infection in Polish fetuses and neonates.
|
28118851 |
2017 |
|
rs5743708
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The inconsistent observations of the immunological and clinical significance of the TLR2 R753Q polymorphism for CMV infection indicates the influence of confounders.
|
27723526 |
2016 |
|
rs5743708
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection.
|
24813591 |
2014 |
|
rs5743708
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In conclusion, homozygosity for TLR2 R753Q SNP is a marker for CMV disease risk, especially for tissue-invasive disease, after liver transplantation.
|
22219347 |
2012 |
|
rs5743708
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A multivariate Cox proportional hazard model demonstrated a trend towards a higher risk of CMV disease among patients who were homozygous for the TLR2 Arg753Gln polymorphism (hazard ratio, 1.91 [95% confidence interval, 0.91-3.40]; P=.08) after adjusting for patient age, CMV serostatus, and allograft rejection.
|
17443468 |
2007 |
|
rs12979860
|
|
|
0.040 |
GeneticVariation |
BEFREE |
IL28B rs12979860 T allele protects against CMV disease in liver transplant recipients in the post-prophylaxis and late period.
|
31165537 |
2019 |
|
rs12979860
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic stem cell transplantation was suggested.
|
30036376 |
2018 |
|
rs12979860
|
|
|
0.040 |
GeneticVariation |
BEFREE |
After adjusting for various clinical covariates, patients harboring T-allele genotypes of interleukin-28B (IL28B) (rs12979860) SNP had lower incidence of CMV infection (adjusted hazard ratio [aHR]: 0.66; 95% confidence interval [CI]: 0.46-0.96; p-value = 0.029).
|
25777542 |
2015 |
|
rs12979860
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The current study was aimed at investigating whether the single nucleotide polymorphism (SNP) (rs12979860), upstream of the IL28B gene, had any effect on the incidence rate and the features of active CMV infection in the Allogeneic stem cell transplantation setting.
|
24374819 |
2014 |
|
rs352140
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our preliminary data suggest that there is no correlation between TLR9 rs352140 polymorphism and frequency of HCMV infection.
|
28143777 |
2017 |
|
rs352140
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Four polymorphisms (-1237T/C, rs5743836; -1486T/C, rs187084; 1174G/A, rs352139; and 2848C/T, rs352140) in the TLR9 gene were genotyped in 72 infants with symptomatic HCMV infection and 70 healthy individuals.
|
27105145 |
2016 |
|
rs1297986
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We analyzed impact of IL28B rs1297986 variants on CMV disease incidence in 743 adult OLT recipients receiving universal prophylaxis.
|
31165537 |
2019 |
|
rs187238
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study examines the impacts of 2 single-nucleotide polymorphisms (SNPs) in the promoter region of the <i>IL-18</i> gene, -607C/A (rs1946518) and -137G/C (rs187238), on the incidence of delayed-onset CMV infection in patients undergoing kidney transplant.
|
31660404 |
2019 |
|
rs1946518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study examines the impacts of 2 single-nucleotide polymorphisms (SNPs) in the promoter region of the <i>IL-18</i> gene, -607C/A (rs1946518) and -137G/C (rs187238), on the incidence of delayed-onset CMV infection in patients undergoing kidney transplant.
|
31660404 |
2019 |
|
rs2596538
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition to the well-known prognostic factors CMV high-risk sero-status of patients and the application of lymphocyte-depleting drugs, the donor MICA rs2596538 G allele carrier status was confirmed by multivariate analyses as novel-independent factor predicting the development of CMV infection/disease during the first year after KTx.
|
29867932 |
2018 |
|
rs368234815
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigate whether the rs12979860 IL28B SNP and the relative rs368234815 (IFNλ4) genotype may affect the incidence of active CMV infection in Autologous stem cell transplantation (Auto-SCT) setting.
|
30036376 |
2018 |
|
rs16944
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate analysis, the IL1B rs16944 TT and TNF rs1799964 TC genotypes were significantly associated with intrauterine CMV infection (aOR = 2.32; 95% CI, 1.11-4.89; p = 0.032, and aOR = 2.17, 95% CI, 1.25-3.77; p = 0.007, respectively).
|
28501927 |
2017 |
|
rs1799964
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate analysis, the IL1B rs16944 TT and TNF rs1799964 TC genotypes were significantly associated with intrauterine CMV infection (aOR = 2.32; 95% CI, 1.11-4.89; p = 0.032, and aOR = 2.17, 95% CI, 1.25-3.77; p = 0.007, respectively).
|
28501927 |
2017 |
|
rs333
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A panel of 11 candidate single nucleotide polymorphisms (SNPs): TNF rs1799964, TNF rs1800629, TNFRSF1A rs4149570, IL1B rs16944, IL1B rs1143634, IL10 rs1800896, IL10RA rs4252279, IL12B rs3212227, CCL2 rs1024611, CCL2 rs13900, CCR5 rs333 was genotyped in 470 infants (72 with confirmed intrauterine CMV infection and 398 uninfected controls), and related to congenital CMV infection, and the outcome.
|
28501927 |
2017 |
|
rs3775290
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped 59 children with symptomatic HCMV infection and 78 healthy individuals for SNPs in the TLR3 (rs3775290, c.1377C>T, F459F; rs3775291, c.1234C>T, L412F; rs3775296, c.-7C>A) and TLR7 (rs179008, c.32A>T, Q11L; rs5741880, c.3+1716G>T) genes.
|
28046022 |
2017 |
|
rs3775291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found an increased frequency of the heterozygous genotype TLR3 L412F in children with HCMV infection compared with uninfected cases.
|
28046022 |
2017 |
|
rs3775296
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, those with a heterozygous genotype of rs3775296 showed an increased relative risk of HCMV infection (P = 0.042), but this association did not reach statistical significance after correction for multiple testing.
|
28046022 |
2017 |