|
rs1447043692
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of genotype TAP1 333 ILE/VAL (61.3%) was significantly higher in DHF compared with control (37%, p = 0.005) or DF (38.9%, p = 0.007) patients.
|
18191725 |
2007 |
|
rs371057322
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of genotype TAP1 333 ILE/VAL (61.3%) was significantly higher in DHF compared with control (37%, p = 0.005) or DF (38.9%, p = 0.007) patients.
|
18191725 |
2007 |
|
rs750898115
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of genotype TAP1 333 ILE/VAL (61.3%) was significantly higher in DHF compared with control (37%, p = 0.005) or DF (38.9%, p = 0.007) patients.
|
18191725 |
2007 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever.
|
20470843 |
2010 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF.
|
21245921 |
2011 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene.
|
22061615 |
2012 |
|
rs2228570
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of T allele of rs2228570 in a dominant mode was significantly higher in DHF cases as compared to DF cases (P=0.034 OR 2.58).
|
22917542 |
2012 |
|
rs7975232
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of C/C genotype of rs7975232 was significantly lower in DEN and DF cases compared to HCs (DEN vs. HCs: Pc=0.0184, OR 0.24; DF cases vs. HCs: Pc=0.028, OR 0.21).
|
22917542 |
2012 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Polymorphisms in the promoter region of CD209 gene (rs735239, rs4804803, rs2287886) were investigated in 112 hospitalized cases of dengue (DEN) and 104 healthy controls to find out whether they are associated with dengue in a Western Indian population.
|
23624202 |
2013 |
|
rs1732778
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs1799964
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The frequency of rs1799964 'C/C' genotype of the TNF gene was found to be significantly higher in all patient groups compared to HCs [HCs vs. DEN, P=0.0054, Pc=0.0162, OR 3.57; HCs vs. DF, P=0.036, OR 2.89; HCs vs. DHF, P=0.0088, Pc=0.0240, OR 5.11].
|
23380141 |
2013 |
|
rs2072136
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs3132468
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study confirms that the MICB rs3132468 and PLCE1 rs3740360 risk genotypes are not only associated with DSS, but are also associated with less severe clinical phenotypes of dengue, as well as with dengue in infants.
|
23536857 |
2013 |
|
rs10774671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs1131454
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs15895
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs1800629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Higher frequency of rs1800629 'G/A' genotype was observed in DHF cases as compared to DF cases.
|
23380141 |
2013 |
|
rs2285932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs2287886
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results revealed a significantly higher frequency of 'G' allele and 'G/G' genotype of rs2287886 and A-A-G haplotype of CD209 gene in DEN compared to healthy controls [For 'G/G' genotype, P=0.0072, Odds ratio (OR) 2.43; For A-A-G haplotype, P=0.0033, OR 2].
|
23624202 |
2013 |
|
rs3740360
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study confirms that the MICB rs3132468 and PLCE1 rs3740360 risk genotypes are not only associated with DSS, but are also associated with less severe clinical phenotypes of dengue, as well as with dengue in infants.
|
23536857 |
2013 |
|
rs735239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggest that rs2287886 G/G genotype of CD209 gene is associated with development of dengue requiring hospitalization while A/A genotype of rs735239 is associated with thrombocytopenia in dengue cases.
|
23624202 |
2013 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Because the -336A/G SNP (rs4804803) polymorphism in the promoter of CD209 modulates DC-SIGN expression, we investigated the putative association of this polymorphism with DENV infection and its pathogenesis.
|
24797508 |
2014 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos.
|
24911936 |
2014 |
|
rs1801274
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos.
|
24911936 |
2014 |
|
rs3132468
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The reported DSS-risk alleles were significantly associated with DSS in Thai patients with dengue (one-sided P = 0.0213 and odds ratio [OR] = 1.58 for rs3132468-C and one-sided P = 0.0252 and OR = 1.49 for rs3765524-C).
|
24884822 |
2014 |