|
rs1732778
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 SNPs (rs1131454), OAS2 SNPs (rs1293762, rs15895 and rs1732778) and OAS3 SNPs (rs2285932 and rs2072136) genes were studied using PCR followed by restriction fragment length polymorphism methods in 30 patients for dengue infection and 40 control group who have no documented evidence of symptomatic dengue.
|
24819159 |
2015 |
|
rs1732778
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs385893
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine the possible association of these SNPs with DHF, 918 Thai patients with dengue [509 patients with DHF and 409 with dengue fever (DF)] were genotyped for five SNPs: rs5745568 in BAK1, rs6141 in THPO, rs6065 in GP1BA, rs739496 in SH2B3, and rs385893 in RCL1.
|
27401010 |
2016 |
|
rs4859584
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped 14 common variants of these candidate genes in 176 patients infected with dengue. rs4859584 and rs8878 (CXCL10) were significantly associated with vascular permeability of dengue infection (P<0.05); while variants of CXCL11 showed moderate significance of association (P=0.0527).
|
25858769 |
2015 |
|
rs739496
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine the possible association of these SNPs with DHF, 918 Thai patients with dengue [509 patients with DHF and 409 with dengue fever (DF)] were genotyped for five SNPs: rs5745568 in BAK1, rs6141 in THPO, rs6065 in GP1BA, rs739496 in SH2B3, and rs385893 in RCL1.
|
27401010 |
2016 |
|
rs5745568
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine the possible association of these SNPs with DHF, 918 Thai patients with dengue [509 patients with DHF and 409 with dengue fever (DF)] were genotyped for five SNPs: rs5745568 in BAK1, rs6141 in THPO, rs6065 in GP1BA, rs739496 in SH2B3, and rs385893 in RCL1.
|
27401010 |
2016 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Polymorphisms in the promoter region of CD209 gene (rs735239, rs4804803, rs2287886) were investigated in 112 hospitalized cases of dengue (DEN) and 104 healthy controls to find out whether they are associated with dengue in a Western Indian population.
|
23624202 |
2013 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever.
|
20470843 |
2010 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Because the -336A/G SNP (rs4804803) polymorphism in the promoter of CD209 modulates DC-SIGN expression, we investigated the putative association of this polymorphism with DENV infection and its pathogenesis.
|
24797508 |
2014 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF).
|
29054571 |
2018 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos.
|
24911936 |
2014 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene.
|
22061615 |
2012 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF.
|
21245921 |
2011 |
|
rs2287886
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results revealed a significantly higher frequency of 'G' allele and 'G/G' genotype of rs2287886 and A-A-G haplotype of CD209 gene in DEN compared to healthy controls [For 'G/G' genotype, P=0.0072, Odds ratio (OR) 2.43; For A-A-G haplotype, P=0.0033, OR 2].
|
23624202 |
2013 |
|
rs735239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggest that rs2287886 G/G genotype of CD209 gene is associated with development of dengue requiring hospitalization while A/A genotype of rs735239 is associated with thrombocytopenia in dengue cases.
|
23624202 |
2013 |
|
rs6065
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To examine the possible association of these SNPs with DHF, 918 Thai patients with dengue [509 patients with DHF and 409 with dengue fever (DF)] were genotyped for five SNPs: rs5745568 in BAK1, rs6141 in THPO, rs6065 in GP1BA, rs739496 in SH2B3, and rs385893 in RCL1.
|
27401010 |
2016 |
|
rs3205166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results revealed a lower carrier frequency of the DDX58 rs3205166 G allele in DEN than in HCs and a higher frequency of the DDX58 rs669260 T/C genotype in DHF than in DF cases (P = 0.043, OR with 95 % CI 3.358 [1.038-10.861]).
|
25850761 |
2015 |
|
rs669260
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results revealed a lower carrier frequency of the DDX58 rs3205166 G allele in DEN than in HCs and a higher frequency of the DDX58 rs669260 T/C genotype in DHF than in DF cases (P = 0.043, OR with 95 % CI 3.358 [1.038-10.861]).
|
25850761 |
2015 |
|
rs1801274
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos.
|
24911936 |
2014 |
|
rs1801274
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A single-nucleotide polymorphism in FcγRIIa (rs1801274) results in altered affinity of the receptor for different subclasses of immunoglobulin G, and is a key player in determining the susceptibility to or protection from severe clinical infection of dengue.
|
26240159 |
2015 |
|
rs1447043692
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of genotype TAP1 333 ILE/VAL (61.3%) was significantly higher in DHF compared with control (37%, p = 0.005) or DF (38.9%, p = 0.007) patients.
|
18191725 |
2007 |
|
rs3739319
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped 193 of the dengue cases using quantitative polymerase chain reaction to the SNP rs3739319.
|
31194647 |
2019 |
|
rs12252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In naturally occurring, genetic loss-of-function studies, MKs from healthy subjects harboring a homozygous mutation in IFITM3 (rs12252-C, a common single-nucleotide polymorphism in areas of the world where DENV is endemic) were significantly more susceptible to DENV infection.
|
30723081 |
2019 |
|
rs1800871
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Under overdominant genetic model, A/G genotype of IL10 rs1800871 was significantly negatively associated with DHF compared to DF cases [p=0.014, OR with 95% CI 0.35 (0.15-0.84)].
|
25890879 |
2015 |
|
rs763780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Frequency of T/C genotype of IL17F rs763780 was significantly lower in DEN group as compared to HC [P=0.033, OR with 95% CI 0.43 (0.19-0.95)].
|
25890879 |
2015 |