Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.090 | GeneticVariation | BEFREE | We tested whether the rs53576 polymorphism in the oxytocin receptor (OXTR) gene accounts for variation in the impact of low social support as a risk factor for depression among mothers during the perinatal period. | 30928624 | 2019 |
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0.090 | GeneticVariation | BEFREE | Given the bi-directional nature of mother-infant influences on maternal mood, we tested the association between both mothers' and infants' OXTR_rs53576 genotype and maternal depression, as assessed through a self-report inventory. | 31755553 | 2019 |
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0.090 | GeneticVariation | BEFREE | A single-nucleotide polymorphism (SNP) of the oxytocin receptor gene (OXTR), rs53576, and a SNP of the CD38 gene, which regulates oxytocin secretion, rs3796863, have been associated with depression and suicidal ideation. | 29860184 | 2018 |
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0.090 | GeneticVariation | BEFREE | These results suggest that rs53576 variants confer vulnerability for depression within the context of interpersonal risk factors, such that youth with the GG genotype may be particularly sensitive to the social consequences resulting from RA. | 28868757 | 2018 |
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0.090 | GeneticVariation | BEFREE | To replicate and extend these findings, we examined whether three literature-based OXTR SNPs (rs2254298, rs53576, rs2268498) interact with childhood maltreatment in the development of clinically diagnosed depression and anxiety disorders. | 28353027 | 2017 |
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0.090 | GeneticVariation | BEFREE | Our results show that the OXTR rs53576 variant modulates the mood in male individuals and may positively correlate with alcohol intake among male suicides, but is not associated with suicide or depression. | 28024273 | 2017 |
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0.090 | GeneticVariation | BEFREE | A case-control association study (225 healthy adults and 188 outpatients with depression) was performed to establish Risk-Combined Genotype (RCG) of the studied variants (OXTR rs53576 and the functional Gβ3 subunit rs5443). | 28499211 | 2017 |
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0.090 | GeneticVariation | BEFREE | Exon 2 methylation was associated with OXTR rs53576 genotype but not with depression</span>. | 25890851 | 2015 |
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0.090 | GeneticVariation | BEFREE | Consistent with an interpersonal perspective on depression, the present study focused on a genetic polymorphism that has been shown to be relevant to social functioning, the rs53576 polymorphism of the oxytocin receptor gene (OXTR). | 24703166 | 2014 |