Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.040 | GeneticVariation | BEFREE | The rs2476601C/T, rs689A/T, and rs7903146C/T polymorphisms were found to be associated with the risk of LADA, thereby indicating that, genetically, LADA could be an admixture of both T1D and T2D. | 30456822 | 2019 |
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0.040 | GeneticVariation | BEFREE | None of the 13 individuals with the rs7903146 TT genotype carried the highest Type 1 diabetes risk HLA genotype, i.e. | 27027642 | 2017 |
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0.040 | GeneticVariation | BEFREE | Two hundred and fifty patients identified as LADA, divided into two subgroups with low (< or = 32 arbitrary units) or high (> 32 units) GADA titre, 620 subjects with Type 2 diabetes [from the Non-Insulin Requiring Autoimmune Diabetes (NIRAD) study cohort of 5330 subjects] in addition to 551 consecutive cases of Type 1 diabetes and 545 normoglycaemic subjects were analysed for the rs12255372 and rs7903146 polymorphisms of the TCF7L2 gene using Taqman. | 20546291 | 2010 |
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0.040 | GeneticVariation | BEFREE | This study found no T1D association with, and no age-of-onset effect from rs7903146. | 17683561 | 2007 |
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0.010 | GeneticVariation | BEFREE | We studied TrialNet participants with newly diagnosed autoimmune type 1 diabetes with available <i>TCF7L2</i> rs4506565 and rs7901695 SNP data (<i>n</i> = 810; median age 13.6 years; range 3.3-58.6). | 29025879 | 2018 |
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0.010 | GeneticVariation | BEFREE | Two hundred and fifty patients identified as LADA, divided into two subgroups with low (< or = 32 arbitrary units) or high (> 32 units) GADA titre, 620 subjects with Type 2 diabetes [from the Non-Insulin Requiring Autoimmune Diabetes (NIRAD) study cohort of 5330 subjects] in addition to 551 consecutive cases of Type 1 diabetes and 545 normoglycaemic subjects were analysed for the rs12255372 and rs7903146 polymorphisms of the TCF7L2 gene using Taqman. | 20546291 | 2010 |