|
rs2207396
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, in hypogonadal men, the rs2207396 variant in ESR1 predicts the risk of type 2 diabetes.
|
23506158 |
2013 |
|
rs1884051
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, nominal association of ESR1 rs1884051 (P=0.011) with T2D in the French cohort replicates a previously observed association in Finns (empirical P=0.024) (http://www.broad.mit.edu/diabetes/).
|
18854778 |
2008 |
|
rs3020314
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs in introns 3 and 4 of the ESR1 gene associated significantly with T2D in the French cohort (rs3020314, rs985694, P = 0.0009-0.001) and with fasting plasma glucose in Swedish men (rs9397456, rs3020314 rs3020317, P = 0.0002-0.0022) after Bonferroni correction for the analysis of 20 SNPs.
|
18854778 |
2008 |
|
rs3020317
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs in introns 3 and 4 of the ESR1 gene associated significantly with T2D in the French cohort (rs3020314, rs985694, P = 0.0009-0.001) and with fasting plasma glucose in Swedish men (rs9397456, rs3020314 rs3020317, P = 0.0002-0.0022) after Bonferroni correction for the analysis of 20 SNPs.
|
18854778 |
2008 |
|
rs9397456
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs in introns 3 and 4 of the ESR1 gene associated significantly with T2D in the French cohort (rs3020314, rs985694, P = 0.0009-0.001) and with fasting plasma glucose in Swedish men (rs9397456, rs3020314 rs3020317, P = 0.0002-0.0022) after Bonferroni correction for the analysis of 20 SNPs.
|
18854778 |
2008 |
|
rs1033182
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The most significant association with type 2 diabetes-ESRD was with rs1033182 in intron 2 (P = 0.013, admixture-adjusted P(a) = 0.021).
|
17327435 |
2007 |
|
rs1709183
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two intron 2 SNPs, rs2431260 (P = 0.015) and rs1709183 (P = 0.019), and a four-SNP haplotype containing these SNPs (P = 0.033) were associated with type 2 diabetes and/or ESRD.
|
17327435 |
2007 |
|
rs2431260
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two intron 2 SNPs, rs2431260 (P = 0.015) and rs1709183 (P = 0.019), and a four-SNP haplotype containing these SNPs (P = 0.033) were associated with type 2 diabetes and/or ESRD.
|
17327435 |
2007 |