|
rs9282541
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The associations between SNPs of TCF7L2 (rs7903146 and rs12255372), SLC16A11 (rs13342232), and ABCA1 (rs9282541) with T2D were analyzed.
|
28101933 |
2017 |
|
rs9282541
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Two SNPs rs10811661 and rs928254 were significantly associated with T2D after adjusting for BMI; rs10811661 in a recessive and rs9282541 in a dominant model.
|
25839936 |
2015 |
|
rs9282541
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The R230C variant of the ATP binding cassette protein A1 (ABCA1) gene is associated with a decreased response to glyburide therapy in patients with type 2 diabetes mellitus.
|
23273975 |
2013 |
|
rs9282541
|
|
|
0.050 |
GeneticVariation |
BEFREE |
No association was found to the only known Native American-specific gene variant previously associated with T2D in a Mexican sample (rs9282541 in ABCA1).
|
22529894 |
2012 |
|
rs9282541
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The R230C ABCA1 variant is associated with type 2 diabetes, particularly of early onset, in the Mexican-Mestizo population.
|
18003760 |
2008 |
|
rs2230806
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In all genetic models, <i>ABCA1</i> rs2230806 had a significant association with prevalence of T2DM: AG (OR=0.78, 95% CI: 0.61-0.98), RG (OR=0.72, 95% CI: 0.51-1.03), DG (OR=0.73, 95% CI: 0.55-0.97), HMG (OR=0.62, 95% CI: 0.41-0.96), and HTG (OR=0.78, 95% CI: 0.61-0.99).
|
29621814 |
2018 |
|
rs2230806
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A Meta-Analysis of the Associations Between the ATP-Binding Cassette Transporter ABCA1 R219K (rs2230806) Polymorphism and the Risk of Type 2 Diabetes in Asians.
|
29621814 |
2018 |
|
rs2230806
|
|
|
0.030 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> This study does not support the association between R219K polymorphism and T2DM-related MCI.
|
28824418 |
2017 |
|
rs2230806
|
|
|
0.030 |
GeneticVariation |
BEFREE |
R219K polymorphism of ABCA1 gene can be considered as a genetic risk factor for T2DM subjects among Malaysians.
|
26451383 |
2015 |
|
rs1800977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, the ABCA1 rs1800977 polymorphism may contribute to the development of T2DM.
|
29439145 |
2018 |
|
rs146292819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, when validated in the CGPS or in the CCHS and CGPS combined (n = 40,600), neither the two loss-of-function mutations (ABCA1 N1800H, ABCG1 g.-376C>T) nor ABCG1 g.-530A>G were associated with type 2 diabetes (P values >0.57 and >0.30, respectively).
|
23139370 |
2012 |
|
rs4149263
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ABCA1 SNP rs4149263 may be associated with the change in atherogenic lipid profile in Type 2 diabetes treated with rosiglitazone.
|
19538231 |
2009 |
|
rs2066714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the present study was to investigate the relationship between R219K, M883I, and R1587K variants of the ATP-binding cassette transporter subfamily A number 1 (ABCA1) gene and response to rosiglitazone treatment in newly diagnosed patients with type 2 diabetes.
|
18215356 |
2008 |
|
rs2230808
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the present study was to investigate the relationship between R219K, M883I, and R1587K variants of the ATP-binding cassette transporter subfamily A number 1 (ABCA1) gene and response to rosiglitazone treatment in newly diagnosed patients with type 2 diabetes.
|
18215356 |
2008 |