Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE Many studies suggest that the <i>small ubiquitin-like modifier 4 (SUMO4)</i> M55V gene polymorphism (rs237025) may be associated with an increased risk of type 2 diabetes mellitus (T2DM). 29163370

2017

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE The meta-analysis demonstrated that the G allele of the SUMO4 M55V polymorphism could be a susceptible risk locus to T2DM, mainly in the Chinese population, while the association in other ethnic population needs to be further validated in studies with relatively large samples. 28494838

2017

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE The small ubiquitin-like modifier 4 (SUMO4) rs237025 polymorphism has been reported to be associated with type 2 diabetes mellitus (T2DM). 28689037

2017

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE SUMO4 163 G>A variation is associated with kidney disease in Indian subjects with type 2 diabetes. 27055882

2016

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE It was found that SUMO4 M55V polymorphism and type-2 diabetes were significantly associated with a possible SUMO4 region to type-2 diabetes susceptibility. 25189908

2015

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE Our study demonstrates significant associations of SUMO4 M55V polymorphism with T1DM in Asian and Caucasian population and with T2DM in Asian population. 22936652

2012

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE The study indicates that the SUMO4 gene M55V variant was not associated with the susceptibility of the type 2 diabetes polymorphism. 20728233

2010

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE This study suggests that in Taiwan the SUMO4 Met 55Val polymorphism is associated with susceptibility to T2DM and Type 2 diabetic patients with GG genotype have worse glycemic control. 19915388

2010

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE SUMO4 Met55Val polymorphism is associated with coronary heart disease in Japanese type 2 diabetes individuals. 19410319

2009

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE CONCLUSIONS-This study indicates that the SUMO4 gene M55V variant is associated with severity of diabetic nephropathy in patients with type 2 diabetes. 17229939

2007

dbSNP: rs237025
rs237025
0.100 GeneticVariation BEFREE These data, together with previous reports, suggest the contribution of the SUMO4 Met55Val polymorphism to both type 1 and type 2 diabetes susceptibility in the Japanese population. 17374705

2007