Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.060 | GeneticVariation | BEFREE | Our meta-analyses provide no evidence of the association of rs5498 with DR in type 2 diabetic patients. | 30419874 | 2018 |
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0.060 | GeneticVariation | BEFREE | Our results revealed that SNP rs5498 in ICAM-1 gene and IVS5-13insC variant in HMGA1 gene were not associated with the susceptibility of DR in the Chinese T2DM cohort. | 26717491 | 2016 |
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0.060 | GeneticVariation | BEFREE | Association between the ICAM-1 K469E polymorphism and diabetic retinopathy in Type 2 diabetes mellitus: a meta-analysis. | 24612665 | 2014 |
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0.060 | GeneticVariation | BEFREE | A number of studies evaluated the association of intracellular adhesion molecule-1 (ICAM-1) K469E (rs5498, A/G) gene polymorphism with diabetic microvascular complications (DMI) including diabetic nephropathy (DN) and diabetic retinopathy (DR) in different populations. | 23922864 | 2013 |
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0.060 | GeneticVariation | BEFREE | A significantly higher frequency of the EE genotype of the K469E polymorphism of the ICAM-1 was found in the patients with PDR compared with those without diabetic retinopathy (OR = 2.0, 95% confidence interval [CI] = 1.1-3.5; P = 0.013), whereas the G241A polymorphism of the ICAM-1 gene failed to yield an association with PDR. | 18942221 | 2008 |
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0.060 | GeneticVariation | BEFREE | Patients with the K469K genotype were more likely to have diabetic retinopathy than patients with the K469E or E469E genotype. | 16759306 | 2006 |
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0.010 | GeneticVariation | BEFREE | To investigate the relationship of the K469E and G241R polymorphisms of the intercellular adhesion molecule 1 (ICAM-1) gene with diabetic retinopathy in Chinese patients with Type 2 diabetes mellitus. | 16759306 | 2006 |