|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study, we analyzed association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (C270T named formerly) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with methamphetamine (MAP) abuse in Japan.
|
15459944 |
2005 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study, we analyzed association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (C270T named formerly) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with methamphetamine (MAP) abuse in Japan.
|
15459944 |
2005 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that the polymorphism (Ile105Val) on exon 5 of the GSTP1 gene may contribute to a vulnerability to psychosis associated with MAP abuse in Japanese population.
|
15729709 |
2005 |
|
rs746682028
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we analyzed association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (C270T named formerly) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with methamphetamine (MAP) abuse in Japan.
|
15459944 |
2005 |
|
rs324420
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The human fatty acid amide hydrolase (FAAH) missense mutation c.385 C-->A, which results in conversion of a conserved proline residue to threonine (P129T), has been associated with street drug use and problem drug abuse.
|
16972078 |
2006 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This result suggests that Val66Met modulates the effect of childhood sexual abuse on the violence of SB.
|
17883407 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This result suggests that Val66Met modulates the effect of childhood sexual abuse on the violence of SB.
|
17883407 |
2008 |
|
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Further, the functional catechol-O-methyltransferase (COMT) Val158Met polymorphism interacted significantly with total CTQ abuse scores to impact perceived dissociation.
|
17608961 |
2008 |
|
rs893924483
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, the functional catechol-O-methyltransferase (COMT) Val158Met polymorphism interacted significantly with total CTQ abuse scores to impact perceived dissociation.
|
17608961 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study we analysed modulating effects of BDNF Val(66)Met polymorphism on the effects of physical maltreatment, rape and childhood sexual abuse on impulsive aggression.
|
19817874 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study we analysed modulating effects of BDNF Val(66)Met polymorphism on the effects of physical maltreatment, rape and childhood sexual abuse on impulsive aggression.
|
19817874 |
2010 |
|
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The functional polymorphism of the catecholamine-O-methyl-transferase (COMT) gene Val158Met significantly modulated the association between sexual abuse and anger-trait level (P = 0.001).
|
20002200 |
2010 |
|
rs9470080
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In AAs, one of the SNPs, rs9470080, moderated the risk of PTSD that was associated with childhood abuse.
|
20393453 |
2010 |
|
rs1885884
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In suicide attempts, HTR2A variants (rs6561333, rs7997012 and rs1885884) were involved through interactions with histories of sexual and physical abuse whereas in mood disorders through one main effect (rs9316235).
|
19381154 |
2010 |
|
rs7997012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In suicide attempts, HTR2A variants (rs6561333, rs7997012 and rs1885884) were involved through interactions with histories of sexual and physical abuse whereas in mood disorders through one main effect (rs9316235).
|
19381154 |
2010 |
|
rs9316235
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In suicide attempts, HTR2A variants (rs6561333, rs7997012 and rs1885884) were involved through interactions with histories of sexual and physical abuse whereas in mood disorders through one main effect (rs9316235).
|
19381154 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the influence of childhood abuse and neglect on positive and negative psychotic-like experiences in adulthood and the potential moderating effect of the BDNF-Val66Met polymorphism.
|
21719879 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met.
|
20703451 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met.
|
20703451 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the influence of childhood abuse and neglect on positive and negative psychotic-like experiences in adulthood and the potential moderating effect of the BDNF-Val66Met polymorphism.
|
21719879 |
2011 |
|
rs1360780
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Given the large effect sizes, rs1360780 could be included into prediction models for depression in individuals exposed to childhood abuse.
|
21654733 |
2011 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, BDNF val(66)met has a significant impact on hippocampal volume independently of childhood abuse and psychiatric status.
|
22832736 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse.
|
21996278 |
2012 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse.
|
21996278 |
2012 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In conclusion, BDNF val(66)met has a significant impact on hippocampal volume independently of childhood abuse and psychiatric status.
|
22832736 |
2012 |