Gene: IL4R ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3024665
rs3024665
IL4R
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs555743307
rs555743307
IL4R
0.040 GeneticVariation BEFREE IL-4Rα gene (I50V) and STAT6 gene (G2964) polymorphisms may play a role in development of eczema; however, the IL-4 gene polymorphism (C-590T) had no relationship with susceptibility to the disease among Saudi children. 27018548

2016
dbSNP: rs555743307
rs555743307
IL4R
0.040 GeneticVariation BEFREE We identified a significant association between IL-4Rα I50V, Q576R polymorphisms and dermatitis susceptibility in AD (p=0.002, <0.001 respectively), whereas no such association was observed in non-AD group (p=0.52, 0.99 respectively). 24742632

2014
dbSNP: rs555743307
rs555743307
IL4R
0.040 GeneticVariation BEFREE The differences in the involvements of loci of promoter region and Ile50Val in interleukin-4 receptor α chain gene between atopic dermatitis and Japanese cedar pollinosis. 21918367

2012
dbSNP: rs555743307
rs555743307
IL4R
0.040 GeneticVariation BEFREE To assess whether genetic variants of TXA2 receptor, IL-4 and IL-4R alpha genes relate to the elevation of serum immunoglobulin E levels in patients with atopic dermatitis (AD), we conducted an association study of genetic polymorphisms of TXA2 receptor (795C/T), IL-4 (-589C/T), and IL-4R alpha (Ile50Val) in a Japanese population (n = 789). 11922633

2002
dbSNP: rs1805011
rs1805011
IL4R
0.020 GeneticVariation BEFREE Our results indicate that rs1805011 polymorphism of IL4Rα gene seems to influence allergy risk, especially mild asthma and atopic dermatitis predisposition in Polish children. 26426602

2016
dbSNP: rs1801275
rs1801275
IL4R
0.020 GeneticVariation BEFREE We identified a significant association between IL-4Rα I50V, Q576R polymorphisms and dermatitis susceptibility in AD (p=0.002, <0.001 respectively), whereas no such association was observed in non-AD group (p=0.52, 0.99 respectively). 24742632

2014
dbSNP: rs1801275
rs1801275
IL4R
0.020 GeneticVariation BEFREE There was no significant association between SNP rs1801275 and eczema. 23480403

2013
dbSNP: rs1805011
rs1805011
IL4R
0.020 GeneticVariation BEFREE Significant associations between SNPs rs1805011 and rs1805015 and eczema were reported in women who had never smoked, but not in those who had ever smoked; the multiplicative interactions, however, were not significant. 23480403

2013
dbSNP: rs1805015
rs1805015
IL4R
0.010 GeneticVariation BEFREE Significant associations between SNPs rs1805011 and rs1805015 and eczema were reported in women who had never smoked, but not in those who had ever smoked; the multiplicative interactions, however, were not significant. 23480403

2013