Gene: BDNF ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.070 GeneticVariation BEFREE Mann-Whitney U, t-tests, and Fisher's exact tests were used to determine if APOE4, BDNF Val66Met, or COMT Val158Met are associated with increased psychiatric symptomatology in people with epilepsy. 30909076

2019
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.070 GeneticVariation BEFREE Our meta-analysis indicated that <i>BDNF</i> rs6265 G>A polymorphism might be involved in epilepsy susceptibility, especially in the Asian population. 29713173

2018
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.070 GeneticVariation BEFREE Results showed significant association between rs6265 T, rs7103411 C, and rs7127507 T and cryptgenic epilepsy</span> risk (p = 0.00003, p = 0.0002, and p = 0.002, respectively) or between rs6265 and rs7103411 and symptomatic epilepsy risk in Malaysian Indians (TT vs. CC, p = 0.004 and T vs. C, p = 0.0002, respectively) as well as between rs6265 T and risk of cryptogenic epilepsy in Malaysian Chinese (p = 0.005). 25876511

2016
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.070 GeneticVariation BEFREE However, whether BDNF Val66Met polymorphism is associated with epilepsy remains controversial. 26000807

2016
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.070 GeneticVariation BEFREE Predisposition to epilepsy in fragile X syndrome: does the Val66Met polymorphism in the BDNF gene play a role? 21890420

2011
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.070 GeneticVariation BEFREE Moreover, the Val66Met polymorphisms did not influence age of epilepsy onset, duration of epilepsy, control of seizures, or extension of the irritative zone. 19896331

2010
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.070 GeneticVariation BEFREE The Val66Met polymorphism in the BDNF gene is associated with epilepsy in fragile X syndrome. 19394799

2009
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.050 GeneticVariation BEFREE Mann-Whitney U, t-tests, and Fisher's exact tests were used to determine if APOE4, BDNF Val66Met, or COMT Val158Met are associated with increased psychiatric symptomatology in people with epilepsy. 30909076

2019
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.050 GeneticVariation BEFREE However, whether BDNF Val66Met polymorphism is associated with epilepsy remains controversial. 26000807

2016
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.050 GeneticVariation BEFREE Predisposition to epilepsy in fragile X syndrome: does the Val66Met polymorphism in the BDNF gene play a role? 21890420

2011
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.050 GeneticVariation BEFREE Moreover, the Val66Met polymorphisms did not influence age of epilepsy onset, duration of epilepsy, control of seizures, or extension of the irritative zone. 19896331

2010
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.050 GeneticVariation BEFREE The Val66Met polymorphism in the BDNF gene is associated with epilepsy in fragile X syndrome. 19394799

2009
dbSNP: rs893924483
rs893924483
BDNF ; BDNF-AS
0.010 GeneticVariation BEFREE Mann-Whitney U, t-tests, and Fisher's exact tests were used to determine if APOE4, BDNF Val66Met, or COMT Val158Met are associated with increased psychiatric symptomatology in people with epilepsy. 30909076

2019
dbSNP: rs7103411
rs7103411
BDNF ; BDNF-AS
0.010 GeneticVariation BEFREE Results showed significant association between rs6265 T, rs7103411 C, and rs7127507 T and cryptgenic epilepsy risk (p = 0.00003, p = 0.0002, and p = 0.002, respectively) or between rs6265 and rs7103411 and symptomatic epilepsy risk in Malaysian Indians (TT vs. CC, p = 0.004 and T vs. C, p = 0.0002, respectively) as well as between rs6265 T and risk of cryptogenic epilepsy in Malaysian Chinese (p = 0.005). 25876511

2016
dbSNP: rs7127507
rs7127507
BDNF ; BDNF-AS
0.010 GeneticVariation BEFREE Results showed significant association between rs6265 T, rs7103411 C, and rs7127507 T and cryptgenic epilepsy risk (p = 0.00003, p = 0.0002, and p = 0.002, respectively) or between rs6265 and rs7103411 and symptomatic epilepsy risk in Malaysian Indians (TT vs. CC, p = 0.004 and T vs. C, p = 0.0002, respectively) as well as between rs6265 T and risk of cryptogenic epilepsy in Malaysian Chinese (p = 0.005). 25876511

2016