|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Genotype data of the 8 PACG single-nucleotide polymorphisms (SNPs) (rs11024102 at PLEKHA7, rs3753841 at COL11A1, rs1015213 located between PCMTD1 and ST18 on Chromosome 8q, rs3816415 at EPDR1, rs1258267 at CHAT, rs736893 at GLIS3, rs7494379 at FERMT2, and rs3739821 mapping in between DPM2 and FAM102A) were available.
|
31377279 |
2019 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
The 8 PACG single nucleotide polymorphisms (SNPs; rs11024102 at PLEKHA7, rs3753841 at COL11A1, rs1015213 located between PCMTD1 and ST18 son chromosome 8q, rs3816415 at EPDR1, rs1258267 at CHAT, rs736893 at GLIS3, rs7494379 at FERMT2, and rs3739821 mapping in between DPM2 and FAM102A) were genotyped by Taqman assays.
|
29310965 |
2018 |
|
rs11024102
|
|
G |
0.790 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.
|
27064256 |
2016 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
The overall result showed that SNPs rs11024102 and rs3753841 were statistically associated with PACG (P < 0.001) in fixed-effects model.
|
25732101 |
2015 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Our study suggests that rs1676486 and rs12138977 in COL11A1 as well as rs216489 and rs11024102 in PLEKHA7 are associated with an increased risk of PAC/PACG in the Han Chinese population, supporting prior reports of the association of COL11A1 and PLEKH7 with angle closure glaucoma.
|
24854855 |
2014 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Recently, three genetic susceptibility loci for primary angle closure glaucoma (PACG) were identified: COL11A1 rs3753841, PCMTD1-ST18 rs1015213, and PLEKHA7 rs11024102.
|
24474268 |
2014 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
SNP rs11024102 showed suggestive association with PACG (p-value 0.035) and no association was found with rs3788317.
|
23840785 |
2013 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Genotype-phenotype analysis of SNPs associated with primary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular biometry in the EPIC-Norfolk Eye Study.
|
23505305 |
2013 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Three loci defined by single nucleotide polymorphisms (SNPs) rs11024102 in PLEKHA7, rs3753841 in COL11A1, and rs1015213 between the PCMTD1 and ST18 genes, recently have been associated with primary angle closure glaucoma (PACG).
|
23847314 |
2013 |
|
rs11024102
|
|
|
0.790 |
GeneticVariation |
BEFREE |
Three susceptibility loci for primary angle-closure glaucoma (PACG) were recently identified: PLEKHA7 rs11024102, COL11A1 rs3753841, and rs1015213 located in the intergenic region between PCMTD1 and ST18.
|
23920366 |
2013 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
Genotype data of the 8 PACG single-nucleotide polymorphisms (SNPs) (rs11024102 at PLEKHA7, rs3753841 at COL11A1, rs1015213 located between PCMTD1 and ST18 on Chromosome 8q, rs3816415 at EPDR1, rs1258267 at CHAT, rs736893 at GLIS3, rs7494379 at FERMT2, and rs3739821 mapping in between DPM2 and FAM102A) were available.
|
31377279 |
2019 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
Three of the 12 SNPs in COL11A1, rs1676486 (<i>P</i>=0.026, OR = 2.089, 95% CI = 1.092-3.996), rs3753841 (<i>P</i>=0.036, OR = 1.886, 95% CI = 1.038-3.426), and rs12138977 (<i>P</i>=0.024, OR = 2.133, 95% CI = 1.104-4.123) were found to have a significant association with PACG.
|
30809385 |
2019 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
The SNP rs3753841 in COL11A1, rs1258267 in CHAT and rs736893 in GLIS3 are associated with PACG in northern Chinese people, and the association of genetic markers manifests a tendency of ethnic diversity.
|
30399154 |
2018 |
|
rs3753841
|
|
G |
0.780 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.
|
27064256 |
2016 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
The overall result showed that SNPs rs11024102 and rs3753841 were statistically associated with PACG (P < 0.001) in fixed-effects model.
|
25732101 |
2015 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
Recently, three genetic susceptibility loci for primary angle closure glaucoma (PACG) were identified: COL11A1 rs3753841, PCMTD1-ST18 rs1015213, and PLEKHA7 rs11024102.
|
24474268 |
2014 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
Three susceptibility loci for primary angle-closure glaucoma (PACG) were recently identified: PLEKHA7 rs11024102, COL11A1 rs3753841, and rs1015213 located in the intergenic region between PCMTD1 and ST18.
|
23920366 |
2013 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
After adjustment for age and sex, SNP rs3753841 was found to be significantly associated with PACG in the Australian cohort (p = 0.017; OR = 1.34).
|
23840785 |
2013 |
|
rs3753841
|
|
|
0.780 |
GeneticVariation |
BEFREE |
Three loci defined by single nucleotide polymorphisms (SNPs) rs11024102 in PLEKHA7, rs3753841 in COL11A1, and rs1015213 between the PCMTD1 and ST18 genes, recently have been associated with primary angle closure glaucoma (PACG).
|
23847314 |
2013 |
|
rs1015213
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Genotype data of the 8 PACG single-nucleotide polymorphisms (SNPs) (rs11024102 at PLEKHA7, rs3753841 at COL11A1, rs1015213 located between PCMTD1 and ST18 on Chromosome 8q, rs3816415 at EPDR1, rs1258267 at CHAT, rs736893 at GLIS3, rs7494379 at FERMT2, and rs3739821 mapping in between DPM2 and FAM102A) were available.
|
31377279 |
2019 |
|
rs1015213
|
|
A |
0.750 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.
|
27064256 |
2016 |
|
rs1015213
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Recently, three genetic susceptibility loci for primary angle closure glaucoma (PACG) were identified: COL11A1 rs3753841, PCMTD1-ST18 rs1015213, and PLEKHA7 rs11024102.
|
24474268 |
2014 |
|
rs1015213
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Three susceptibility loci for primary angle-closure glaucoma (PACG) were recently identified: PLEKHA7 rs11024102, COL11A1 rs3753841, and rs1015213 located in the intergenic region between PCMTD1 and ST18.
|
23920366 |
2013 |
|
rs1015213
|
|
|
0.750 |
GeneticVariation |
BEFREE |
In our study, rs1015213 (located in the intergenic region between PCMTD1 and ST18) was associated significantly with PAC/PACG, confirming prior reports of an association between this region and angle closure glaucoma.
|
23847314 |
2013 |
|
rs1015213
|
|
|
0.750 |
GeneticVariation |
BEFREE |
This study suggests that primary angle closure glaucoma susceptibility at the PCMTD1-ST18 locus may be partly explained by an association between rs1015213 and ACD in European populations.
|
23505305 |
2013 |