|
rs5186
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We did not observe associations between hypertension and rs1799752 (<i>P</i>=0.422), rs699 (<i>P</i>=0.36), rs5186 (<i>P</i>=0.49), and rs1799998 (<i>P</i>=0.71).
|
31511791 |
2019 |
|
rs5186
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Angiotensin II Type 1 Receptor rs5186 Gene Variant Predicts Incident NAFLD and Associated Hypertension: Role of Dietary Fat-Induced Pro-Inflammatory Cell Activation.
|
30920415 |
2019 |
|
rs5186
|
|
|
0.060 |
GeneticVariation |
BEFREE |
An association was found between rs5186, rs699, and hypertension under allele contrast and homozygous codominant models (odds ratio, 1.63 [95% confidence interval, 1.04-2.54] and 4.01 [95% confidence interval, 1.17-13.80] for rs5186, respectively; and 1.80 [95% confidence interval, 1.13-2.87] for rs699).
|
29520984 |
2018 |
|
rs5186
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This study examined the SNPs AGT rs699 (Met235Thr), ADD1 rs4961 (Gly460Trp), NPPA rs5063 (Val32Met), GPX1 rs1050450 (Pro198Leu), and AGTR1 rs5186 (A1166C) in relation to hypertension and salt sensitivity.
|
27480094 |
2017 |
|
rs5186
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A polymorphism in the angiotensin II type 1 receptor gene (AGTR1/rs5186) has been associated with an increased risk for arterial stiffness, hypertension, and ischemic stroke.
|
24981111 |
2014 |
|
rs5186
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We assessed whether distributions of 3 single nucleotide polymorphisms in genes coding for components of G protein signaling pathways that have been associated with hypertension differ between women with preeclampsia and normotensive pregnant women; the G protein β3 subunit gene (GNB3) C825T polymorphism (rs5443), the angiotensin II type 1 receptor gene (AGTR1) 3'UTR A1166C polymorphism (rs5186), and the regulator of G protein signaling 2 gene (RGS2) 3'UTR C1114G polymorphism (rs4606).
|
23339167 |
2013 |
|
rs5182
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Moreover, among the eight SNPs not individually associated with hypertension (rs12631819, rs2920502, rs1175543, and rs2972164 in the PPARG gene, and rs2638360, rs1492100, rs5182, and rs275646 in the AGTR1 gene), the two-locus model involving rs12631819 and rs5182 demonstrated increased susceptibility to hypertension, and the five-locus model involving rs12631819, rs2920502, rs2972164, rs5182, and rs2638360 demonstrated a significantly decreased risk of hypertension.
|
29266977 |
2018 |
|
rs5182
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Although the AGTR1 SNP did not show any association with WMLs, the interaction of the AGT rs699 and AGTR1 rs5182 SNPs with WMLs was significant before (P = 0.03) and after adjustment for hypertension (P = 0.045).
|
24622918 |
2014 |
|
rs5182
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The results suggest that the rs5182 gene polymorphism could be involved in the risk of developing hypertension in Mexican individuals.
|
21846682 |
2012 |
|
rs2638360
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, among the eight SNPs not individually associated with hypertension (rs12631819, rs2920502, rs1175543, and rs2972164 in the PPARG gene, and rs2638360, rs1492100, rs5182, and rs275646 in the AGTR1 gene), the two-locus model involving rs12631819 and rs5182 demonstrated increased susceptibility to hypertension, and the five-locus model involving rs12631819, rs2920502, rs2972164, rs5182, and rs2638360 demonstrated a significantly decreased risk of hypertension.
|
29266977 |
2018 |
|
rs2933249
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, individuals with T allele of rs2933249 in the AGTR1 gene displayed a significantly decreased risk of hypertension.
|
29266977 |
2018 |
|
rs12695895
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present results indicate that rs12695895 might be a genetic marker for EH and Hap4 (AGGACTT) was associated with hypertension in Han Chinese population.
|
19833117 |
2010 |
|
rs911154679
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Constitutively activated GRK4 gene variants (R65L, A142V, and A486V), by themselves or by their interaction with other genes involved in blood pressure regulation, are associated with essential hypertension and/or salt-sensitive hypertension in several ethnic groups.
|
20153824 |
2010 |
|
rs553350297
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of the A640G gene variation with the presence and extent of CAD was not only identified in the total sample, but was even stronger in various high risk subpopulations of younger individuals (e.g. with hypertension with or without increased apolipoprotein B plasma levels).
|
10488959 |
1999 |